Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 2/20 | 0.56 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 9/20 | 0.52 |
| ▸ | RAB9A | P51151 | 9/20 | 0.52 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA3 | P07451 | 1/20 | 0.51 |
| ▸ | CA4 | P22748 | 1/20 | 0.51 |
| ▸ | CA6 | P23280 | 1/20 | 0.51 |
| ▸ | CA7 | P43166 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.51 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.51 |
| ▸ | GLA | P06280 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.51 |
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046282 | 0.87 | MAOB (0.69) | MAOBTP53NPC1RAB9ACA12 | |
| SCHEMBL18535597 | 0.87 | MAOB (0.62) | MAOBTP53NPC1RAB9ACA12 | |
| SCHEMBL18535513 | 0.86 | MAOB (0.61) | MAOBTP53NPC1RAB9ACA12 | |
| SCHEMBL22625283 | 0.84 | MAOB (0.58) | MAOBTP53NPC1RAB9ACA12 | |
| SCHEMBL2167401 | 0.83 | MIF (0.71) | MAOBTP53NPC1RAB9AKDM4E | |
| SCHEMBL23713537 | 0.83 | MAOB (0.58) | MAOBTP53NPC1RAB9ACA12 | |
| SCHEMBL18535458 | 0.83 | NPC1 (0.71) | MAOBTP53NPC1RAB9ACA12 | |
| SCHEMBL23713486 | 0.82 | TP53 (0.58) | MAOBTP53NPC1RAB9ACA12 | |
| SCHEMBL6689326 | 0.82 | TP53 (0.74) | MAOBTP53NPC1RAB9AKDM4E | |
| SCHEMBL23713470 | 0.81 | MIF (0.68) | MAOBTP53NPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210363122-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | MERCK PATENT GMBH (DE) | 2021-11-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210363122-A1 | COMPOUNDS FOR OPTICALLY ACTIVE DEVICES | PDE6C, ALDH1A2, PDE6A | MAOB 212/4885TP53 4837/4885NPC1 2482/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.