Sugi Predict

Sugi Predict / Compounds / SCHEMBL2167401

SCHEMBL2167401

SCHEMBL2167401

CCCCOc1ccc(-c2cc3ccc(O)cc3oc2=O)cc1

nearest known ligand 0.71

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MIF P14174 10/20 0.71
▸ NPC1 O15118 4/20 0.71
▸ RAB9A P51151 3/20 0.71
▸ MEN1 O00255 2/20 0.71
▸ KMT2A Q03164 2/20 0.71
▸ ERAP1 Q9NZ08 2/20 0.71
▸ RXFP1 Q9HBX9 1/20 0.71
▸ SIRT3 Q9NTG7 1/20 0.71
▸ ESR2 Q92731 2/20 0.67
▸ TDP1 Q9NUW8 2/20 0.61
▸ KDM4E B2RXH2 2/20 0.61
▸ ALDH1A1 P00352 2/20 0.61
▸ GLA P06280 1/20 0.61
▸ POLB P06746 1/20 0.61
▸ GAA P10253 1/20 0.61
▸ HPGD P15428 1/20 0.61
▸ NPSR1 Q6W5P4 1/20 0.61
▸ TP53 P04637 1/20 0.59
▸ ATM Q13315 1/20 0.58
▸ TLR9 Q9NR96 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23713470 0.98 MIF (0.68) MIFNPC1RAB9AMEN1KMT2A
SCHEMBL18535513 0.88 MAOB (0.61) MIFNPC1RAB9AMEN1KMT2A
SCHEMBL23713486 0.87 TP53 (0.58) MIFNPC1RAB9AMEN1KMT2A
SCHEMBL18535597 0.86 MAOB (0.62) MIFNPC1RAB9AMEN1KMT2A
SCHEMBL24046282 0.86 MAOB (0.69) MIFNPC1RAB9AMEN1KMT2A
SCHEMBL18535458 0.85 NPC1 (0.71) MIFNPC1RAB9AMEN1KMT2A
SCHEMBL6689326 0.84 TP53 (0.74) NPC1RAB9AMEN1KMT2AESR2
SCHEMBL24046151 0.83 MAOB (0.56) MIFNPC1RAB9AMEN1KMT2A
SCHEMBL21116523 0.83 ESR2 (0.64) MIFNPC1RAB9AMEN1KMT2A
SCHEMBL949458 0.83 MIF (1.00) MIFNPC1RAB9AMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11702396-B2 Hydrophobic compounds for optically active devices Johnson & Johnson Surgical Vision, Inc. (US) 2023-07-18 — — US disclosed
US-11702396-B2 Hydrophobic compounds for optically active devices Johnson & Johnson Surgical Vision, Inc. (US) 2023-07-18 — — US disclosed
EP-3728339-B1 COMPOSITION FOR OPHTHALMOLOGICAL PRODUCTS AMO Ireland (IE) 2022-07-06 — — EP disclosed
US-20210363122-A1 COMPOUNDS FOR OPTICALLY ACTIVE DEVICES MERCK PATENT GMBH (DE) 2021-11-25 — — US disclosed
US-11078177-B2 Compounds for optically active devices MERCK PATENT GMBH (DE) 2021-08-03 — — US disclosed
US-11001576-B2 Compounds for optically active devices MERCK PATENT GMBH (DE) 2021-05-11 — — US disclosed
EP-3583102-B1 HYDROPHOBIC COMPOUNDS FOR OPTICALLY ACTIVE DEVICES MERCK PATENT GMBH (DE) 2020-11-04 — — EP disclosed
EP-3583101-B1 BIS-COMPOUNDS FOR OPTICALLY ACTIVE DEVICES MERCK PATENT GMBH (DE) 2020-10-28 — — EP disclosed
US-20200062739-A1 COMPOUNDS FOR OPTICALLY ACTIVE DEVICES MERCK PATENT GMBH (DE) 2020-02-27 — — US disclosed
US-10457658-B2 Compounds for optically active devices MERCK PATENT GMBH (DE) 2019-10-29 — — US disclosed
EP-3133065-A1 COMPOUNDS FOR OPTICALLY ACTIVE DEVICES Merck Patent GmbH (DE) 2017-02-22 — — EP disclosed
US-8592007-B2 Liquid-crystal display MERCK PATENT GMBH (DE) 2013-11-26 — — US disclosed
EP-2340292-B1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2013-05-29 — — EP disclosed
EP-2340292-B1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2013-05-29 — — EP disclosed
US-20110205482-A1 LIQUID-CRYSTAL DISPLAY MERCH PATENT GESELLSCHAFT MIT BESCHRANKTE HAFTUNG (DE) 2011-08-25 — — US disclosed
US-20110205482-A1 LIQUID-CRYSTAL DISPLAY MERCH PATENT GESELLSCHAFT MIT BESCHRANKTE HAFTUNG (DE) 2011-08-25 — — US disclosed
US-20110205482-A1 LIQUID-CRYSTAL DISPLAY MERCH PATENT GESELLSCHAFT MIT BESCHRANKTE HAFTUNG (DE) 2011-08-25 — — US disclosed
EP-2340292-A1 LIQUID CRYSTAL DISPLAY Merck Patent GmbH (DE) 2011-07-06 — — EP disclosed
WO-2010049044-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2010-05-06 — — WO disclosed
WO-2010049044-A1 LIQUID CRYSTAL DISPLAY MERCK PATENT GMBH (DE) 2010-05-06 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210363122-A1 COMPOUNDS FOR OPTICALLY ACTIVE DEVICES PDE6C, ALDH1A2, PDE6A MIF 1378/4885NPC1 2482/4885RAB9A 930/4885
US-11702396-B2 Hydrophobic compounds for optically active devices UACA, CRYZ, TRPA1 MIF 951/4885NPC1 1051/4885RAB9A 1916/4885
US-10457658-B2 Compounds for optically active devices PDE6C, ALDH1A2, PDE6A MIF 1378/4885NPC1 2482/4885RAB9A 930/4885
US-20110205482-A1 LIQUID-CRYSTAL DISPLAY VCL, LPXN, LCP1 MIF 3165/4885NPC1 4181/4885RAB9A 2121/4885
US-20200062739-A1 COMPOUNDS FOR OPTICALLY ACTIVE DEVICES PDE6C, PDE6A, PDE6D MIF 2239/4885NPC1 2727/4885RAB9A 1119/4885
US-11078177-B2 Compounds for optically active devices PDE6C, ALDH1A2, PDE6A MIF 1378/4885NPC1 2482/4885RAB9A 930/4885
US-11001576-B2 Compounds for optically active devices PDE6C, PDE6A, PDE6D MIF 2239/4885NPC1 2727/4885RAB9A 1119/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.