SCHEMBL2404652

SCHEMBL2404652

C=C(C)C(=O)OCCC[Si](O[Si](C)(C)CCC(F)(F)F)(O[Si](C)(C)CCC(F)(F)F)O[Si](C)(C)CCC(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.42
THRB P10828 1/20 0.36
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27361285 0.92 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL27428980 0.88 TSHR (0.41) TSHRTHRBPOLBAPEX1HTT
SCHEMBL13334705 0.86 TSHR (0.39) TSHRTHRBPOLBAPEX1HTT
SCHEMBL14498182 0.85 TSHR (0.41) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11074263 0.83 TSHR (0.44) TSHRTHRBPOLBAPEX1HTT
SCHEMBL12870020 0.83 TSHR (0.54) TSHRTHRBPOLBAPEX1HTT
SCHEMBL9576291 0.83 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL30825544 0.83 TSHR (0.46) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11073250 0.82 TSHR (0.45) TSHRTHRBPOLBAPEX1HTT
SCHEMBL11075328 0.82 TSHR (0.45) TSHRTHRBPOLBAPEX1HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12492294-B2 Biocompatible porous materials and methods of manufacture and use Poragen LLC (US) 2025-12-09 US disclosed
US-12116468-B2 Composite particles comprising a hydrophobic dye and an amphiphilic block copolymer and use thereof in optical applications COLOURSMITH LABS INC. (CA) 2024-10-15 US disclosed
US-20240034853-A1 BIOCOMPATIBLE POROUS MATERIALS AND METHODS OF MANUFACTURE AND USE Renovo Concepts, Inc. 2024-02-01 US disclosed
US-11692075-B2 Biocompatible porous materials and methods of manufacture and use Poragen LLC (US) 2023-07-04 US disclosed
EP-4125734-A1 BIOCOMPATIBLE POROUS MATERIALS AND METHODS OF MANUFACTURE AND USE Poragen LLC (US) 2023-02-08 EP disclosed
US-20220235197-A1 COMPOSITE PARTICLES COMPRISING A HYDROPHOBIC DYE AND AN AMPHIPHILIC BLOCK COPOLYMER AND USE THEREOF IN OPTICAL APPLICATIONS COLOURSMITH LABS INC. (CA) 2022-07-28 US disclosed
EP-3976715-A1 COMPOSITE PARTICLES COMPRISING A HYDROPHOBIC DYE AND AN AMPHIPHILIC BLOCK COPOLYMER AND USE THEREOF IN OPTICAL APPLICATIONS Coloursmith Labs Inc. (CA) 2022-04-06 EP disclosed
US-20220033611-A1 BIOCOMPATIBLE POROUS MATERIALS AND METHODS OF MANUFACTURE AND USE Renovo Concepts, Inc. 2022-02-03 US disclosed
US-11149127-B1 Biocompatible porous materials and methods of manufacture and use Poragen LLC (US) 2021-10-19 US disclosed
WO-2021195571-A1 BIOCOMPATIBLE POROUS MATERIALS AND METHODS OF MANUFACTURE AND USE Poragen LLC (US) 2021-09-30 WO disclosed
US-20120252925-A1 Silicone Hydrogel Contact Lens COOPERVISION INTERNATIONAL HOLDING COMPANY, LP (BB) 2012-10-04 US disclosed
US-20110211158-A1 Long-Wearable Soft Contact Lens COOPERVISION INTERNATIONAL LIMITED (GB) 2011-09-01 US disclosed
EP-1243960-B1 SOFT CONTACT LENS CAPABLE OF BEING WORN FOR A LONG PERIOD ASAHIKASEI AIME CO LTD (JP) 2009-08-26 EP disclosed
US-20070066706-A1 Silicone hydrogel contact lens COOPERVISION, INC. (US) 2007-03-22 US disclosed
US-20060063852-A1 Silicone hydrogel contact lens ASAHIKASEI AIME CO. LTD. (JP) 2006-03-23 US disclosed
US-6867245-B2 Long wearable soft contact lens ASAHIKASEI AIME CO., LTD. (JP) 2005-03-15 US disclosed
US-20040192872-A1 Long-wearable soft contact lens ASAHIKASEI AIME CO., LTD (JP) 2004-09-30 US disclosed
EP-1243960-A1 SOFT CONTACT LENS CAPABLE OF BEING WORN FOR A LONG PERIOD ASAHIKASEI AIME CO., Ltd. (JP) 2002-09-25 EP disclosed
US-20020016383-A1 Long wearable soft contact lens COOPERVISION INTERNATIONAL LIMITED (GB) 2002-02-07 US disclosed
US-4727172-A REACTING AN ORGANOSILICON HALOMAGNESIUM SALT WITH AN ORGANOSILICON COMPOUND SHIN-ETSU CHEMICAL CO., LTD. (JP) 1988-02-23 US disclosed