Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.44 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27428980 | 0.93 | TSHR (0.41) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL2404652 | 0.92 | TSHR (0.42) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL13334705 | 0.88 | TSHR (0.39) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL64810 | 0.88 | TSHR (0.55) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL26561519 | 0.86 | TSHR (0.53) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10329836 | 0.86 | TSHR (0.47) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL14130481 | 0.85 | TSHR (0.56) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL10329839 | 0.84 | TSHR (0.45) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17718723 | 0.83 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT | |
| SCHEMBL17059112 | 0.83 | TSHR (0.50) | TSHRTHRBPOLBAPEX1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1070494-C | Monomeric units useful for reducing modulus of low water polymeric silicone composition | BAUSCH & LOMB (US) | 2001-09-05 | — | — | CN | disclosed |
| CN-1204338-A | Monomers for reducing modulus of low water polysiloxane compositions | BAUSCH & LOMB (US) | 1999-01-06 | — | — | CN | disclosed |