Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | DPP4 | P27487 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | FYN | P06241 | 3/20 | 0.35 |
| ▸ | XDH | P47989 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.33 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.33 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.33 |
| ▸ | TUBB | P07437 | 1/20 | 0.33 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.33 |
| ▸ | TUBA1B | P68363 | 1/20 | 0.33 |
| ▸ | TUBA4A | P68366 | 1/20 | 0.33 |
| ▸ | TUBB4B | P68371 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6608408 | 0.95 | PDE4A (0.36) | PDE4APDE4BPDE4CPDE4DDPP4 | |
| SCHEMBL30918494 | 0.89 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DDPP4 | |
| SCHEMBL3930071 | 0.89 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4DDPP4 | |
| SCHEMBL15969312 | 0.81 | KCNN4 (0.33) | FYNXDHALDH1A1EGFR | |
| SCHEMBL6606565 | 0.79 | ALDH1A1 (0.33) | FYNALDH1A1TUBB4ATUBBTUBA3C | |
| SCHEMBL21749946 | 0.79 | S1PR1 (0.44) | PDE4APDE4BPDE4CPDE4DDPP4 | |
| SCHEMBL24047005 | 0.79 | SMN1; SMN2 (0.36) | DPP4XDHALDH1A1P2RX3P2RX2 | |
| SCHEMBL6610520 | 0.77 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DDPP4 | |
| SCHEMBL4142722 | 0.77 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DDPP4 | |
| SCHEMBL4148399 | 0.77 | PDE4A (0.38) | PDE4APDE4BPDE4CPDE4DDPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |