Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | XDH | P47989 | 1/20 | 0.36 |
| ▸ | MYC | P01106 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | TNFSF11 | O14788 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | DPP4 | P27487 | 2/20 | 0.33 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.32 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9686722 | 0.90 | SMN1; SMN2 (0.40) | SMN1; SMN2MYCCYP3A4TNFSF11DPP4 | |
| SCHEMBL9784763 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2MYCCYP3A4TNFSF11DPP4 | |
| SCHEMBL4133838 | 0.81 | SMN1; SMN2 (0.37) | SMN1; SMN2MYCCYP3A4TNFSF11DPP4 | |
| SCHEMBL15273810 | 0.79 | ALDH1A1 (0.38) | SMN1; SMN2TNKS2ALDH1A1RXFP1 | |
| SCHEMBL25259332 | 0.79 | TNKS2 (0.37) | SMN1; SMN2TNFSF11TNKS2ALDH1A1RXFP1 | |
| SCHEMBL24046764 | 0.79 | PDE4A (0.39) | XDHDPP4ALDH1A1P2RX3P2RX2 | |
| SCHEMBL16748702 | 0.75 | ALDH1A1 (0.44) | SMN1; SMN2CYP3A4ALDH1A1KMT2A | |
| SCHEMBL11843092 | 0.74 | ALOX5 (0.43) | CYP3A4TNKS2ALDH1A1 | |
| SCHEMBL4135777 | 0.74 | HSD11B1 (0.33) | DPP4ALDH1A1 | |
| SCHEMBL6608408 | 0.73 | PDE4A (0.36) | XDHDPP4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |