Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 8/20 | 0.54 |
| ▸ | CSNK2B | P67870 | 8/20 | 0.54 |
| ▸ | CSNK2A1 | P68400 | 8/20 | 0.54 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.48 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.48 |
| ▸ | TERT | O14746 | 5/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | NQO1 | P15559 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.37 |
| ▸ | CYP1B1 | Q16678 | 3/20 | 0.37 |
| ▸ | CSNK2A3 | Q8NEV1 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046880 | 0.86 | CSNK2A2 (0.55) | CSNK2A2CSNK2BCSNK2A1CYSLTR2CYSLTR1 | |
| SCHEMBL24046876 | 0.85 | CSNK2A2 (0.54) | CSNK2A2CSNK2BCSNK2A1CYSLTR2CYSLTR1 | |
| SCHEMBL24046885 | 0.85 | ALDH1A1 (0.44) | CSNK2A2CSNK2BCSNK2A1CYSLTR2CYSLTR1 | |
| SCHEMBL24046873 | 0.82 | CSNK2A2 (0.51) | CSNK2A2CSNK2BCSNK2A1CYSLTR2CYSLTR1 | |
| SCHEMBL24046990 | 0.78 | CSNK2A2 (0.50) | CSNK2A2CSNK2BCSNK2A1CYSLTR2CYSLTR1 | |
| SCHEMBL24046755 | 0.76 | CSNK2A2 (0.73) | CSNK2A2CSNK2BCSNK2A1TERTMEN1 | |
| SCHEMBL24046883 | 0.73 | CSNK2A2 (0.51) | CSNK2A2CSNK2BCSNK2A1CYSLTR2CYSLTR1 | |
| SCHEMBL24046752 | 0.73 | CSNK2A2 (0.78) | CSNK2A2CSNK2BCSNK2A1TERTMEN1 | |
| SCHEMBL24046998 | 0.72 | CSNK2A2 (0.72) | CSNK2A2CSNK2BCSNK2A1TERTBRD4 | |
| SCHEMBL24046928 | 0.72 | CSNK2A2 (0.65) | CSNK2A2CSNK2BCSNK2A1TERTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |