Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 11/20 | 0.65 |
| ▸ | PARP1 | P09874 | 5/20 | 0.60 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.60 |
| ▸ | GABRP | O00591 | 5/20 | 0.60 |
| ▸ | GABRD | O14764 | 5/20 | 0.60 |
| ▸ | GABRA1 | P14867 | 5/20 | 0.60 |
| ▸ | GABRB1 | P18505 | 5/20 | 0.60 |
| ▸ | GABRG2 | P18507 | 5/20 | 0.60 |
| ▸ | GABRB3 | P28472 | 5/20 | 0.60 |
| ▸ | GABRA5 | P31644 | 5/20 | 0.60 |
| ▸ | GABRA3 | P34903 | 5/20 | 0.60 |
| ▸ | GABRA2 | P47869 | 5/20 | 0.60 |
| ▸ | GABRB2 | P47870 | 5/20 | 0.60 |
| ▸ | GABRA4 | P48169 | 5/20 | 0.60 |
| ▸ | GABRE | P78334 | 5/20 | 0.60 |
| ▸ | GABRA6 | Q16445 | 5/20 | 0.60 |
| ▸ | GABRG1 | Q8N1C3 | 5/20 | 0.60 |
| ▸ | GABRG3 | Q99928 | 5/20 | 0.60 |
| ▸ | GABRQ | Q9UN88 | 5/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL311918 | 0.82 | TNKS (0.76) | TNKSPARP1TNKS2SMN1; SMN2GABRP | |
| SCHEMBL24046904 | 0.81 | TNKS (0.61) | TNKSPARP1TNKS2SMN1; SMN2GABRP | |
| SCHEMBL2032421 | 0.79 | TNKS (1.00) | TNKSPARP1TNKS2SMN1; SMN2GABRP | |
| SCHEMBL103839 | 0.77 | TNKS (1.00) | TNKSPARP1TNKS2SMN1; SMN2GABRP | |
| SCHEMBL23070093 | 0.77 | TNKS (0.93) | TNKSPARP1TNKS2SMN1; SMN2GABRP | |
| Flavone SCHEMBL29155354 | 0.77 | TNKS (0.93) | TNKSPARP1TNKS2SMN1; SMN2GABRP | |
| Flavone SCHEMBL31316377 | 0.76 | TNKS (1.00) | TNKSPARP1TNKS2SMN1; SMN2GABRP | |
| Flavone SCHEMBL15676601 | 0.76 | TNKS (1.00) | TNKSPARP1TNKS2SMN1; SMN2GABRP | |
| Flavone SCHEMBL18879 | 0.76 | TNKS (1.00) | TNKSPARP1TNKS2SMN1; SMN2GABRP | |
| Flavone SCHEMBL30542161 | 0.76 | TNKS (1.00) | TNKSPARP1TNKS2SMN1; SMN2GABRP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |