Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNKS | O95271 | 12/20 | 0.61 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.56 |
| ▸ | PARP1 | P09874 | 5/20 | 0.56 |
| ▸ | TNKS2 | Q9H2K2 | 5/20 | 0.56 |
| ▸ | HPGD | P15428 | 5/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 4/20 | 0.56 |
| ▸ | PLA2G4A | P47712 | 4/20 | 0.56 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.56 |
| ▸ | GABRP | O00591 | 3/20 | 0.56 |
| ▸ | GABRD | O14764 | 3/20 | 0.56 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.56 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.56 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.56 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.56 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.56 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.56 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.56 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24046864 | 0.84 | TNKS (0.71) | TNKSSMN1; SMN2PARP1TNKS2HPGD | |
| SCHEMBL24046875 | 0.83 | MAOB (0.60) | TNKSSMN1; SMN2TNKS2HPGDCYP3A4 | |
| SCHEMBL24046906 | 0.81 | TNKS (0.65) | TNKSSMN1; SMN2PARP1TNKS2HPGD | |
| SCHEMBL24046902 | 0.80 | TNKS (0.64) | TNKSSMN1; SMN2PARP1TNKS2HPGD | |
| SCHEMBL2032421 | 0.76 | TNKS (1.00) | TNKSSMN1; SMN2PARP1TNKS2HPGD | |
| SCHEMBL24047003 | 0.74 | ABCB1 (0.61) | SMN1; SMN2HPGDCYP3A4RAB9ANPC1 | |
| SCHEMBL1095325 | 0.74 | ACMSD (0.58) | — | |
| SCHEMBL23070093 | 0.74 | TNKS (0.93) | TNKSSMN1; SMN2PARP1TNKS2HPGD | |
| Flavone SCHEMBL15676601 | 0.73 | TNKS (1.00) | TNKSSMN1; SMN2PARP1TNKS2HPGD | |
| Flavone SCHEMBL18879 | 0.73 | TNKS (1.00) | TNKSSMN1; SMN2PARP1TNKS2HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021236578-A1 | CHROMEN-4-ONE DERIVATIVES, SUCH AS E.G. FLAVONES, FOR USE AS CK2 INHIBITORS FOR THE TREATMENT OF NEUROINFLAMMATION | SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2021-11-25 | — | — | WO | disclosed |