Flavone

Flavone

SCHEMBL18879

O=c1cc(-c2ccccc2)oc2ccccc12

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TNKS O95271 9/20 1.00
GABRP O00591 5/20 1.00
GABRD O14764 5/20 1.00
GABRA1 P14867 5/20 1.00
GABRB1 P18505 5/20 1.00
GABRG2 P18507 5/20 1.00
GABRB3 P28472 5/20 1.00
GABRA5 P31644 5/20 1.00
GABRA3 P34903 5/20 1.00
GABRA2 P47869 5/20 1.00
GABRB2 P47870 5/20 1.00
GABRA4 P48169 5/20 1.00
GABRE P78334 5/20 1.00
GABRA6 Q16445 5/20 1.00
GABRG1 Q8N1C3 5/20 1.00
GABRG3 Q99928 5/20 1.00
GABRQ Q9UN88 5/20 1.00
PARP1 P09874 4/20 1.00
TNKS2 Q9H2K2 4/20 1.00
NPC1 O15118 2/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Flavone SCHEMBL28248986 1.00 TNKS (1.00) TNKSGABRPGABRDGABRA1GABRB1
Flavone SCHEMBL15676601 1.00 TNKS (1.00) TNKSGABRPGABRDGABRA1GABRB1
Flavone SCHEMBL31316377 1.00 TNKS (1.00) TNKSGABRPGABRDGABRA1GABRB1
Flavone SCHEMBL30542161 1.00 TNKS (1.00) TNKSGABRPGABRDGABRA1GABRB1
Flavone SCHEMBL1660769 0.98 TNKS (0.96) TNKSGABRPGABRDGABRA1GABRB1
Flavone SCHEMBL8069086 0.98 TNKS (0.96) TNKSGABRPGABRDGABRA1GABRB1
Flavone SCHEMBL31099335 0.98 TNKS (0.96) TNKSGABRPGABRDGABRA1GABRB1
Flavone SCHEMBL3090011 0.98 TNKS (0.96) TNKSGABRPGABRDGABRA1GABRB1
Flavone SCHEMBL6908621 0.98 TNKS (0.96) TNKSGABRPGABRDGABRA1GABRB1
Flavone SCHEMBL9530678 0.98 TNKS (0.96) TNKSGABRPGABRDGABRA1GABRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 116147 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3848462-B1 BAICALEIN- AND SCUTELLAREIN-SYNTHESIZING MICROORGANISM, PREPARATION METHOD, AND APPLICATIONS THEREOF CAS CENTER FOR EXCELLENCE IN MOLECULAR PLANT SCIENCES (CN) 2026-05-27 EP claimed
CN-121496038-B Screening method and application of carbapenem-resistant klebsiella pneumoniae traditional Chinese medicine inhibitor THE SECOND HOSPITAL OF DALIAN MEDICAL UNIVERSITY (CN) 2026-05-26 CN claimed
CN-122081102-A Microbial strain for de novo synthesis of gardenia flavin B and application of microbial strain in production of polymethoxy flavonoid compound 2026-05-26 CN claimed
CN-122075558-A Application of semen oroxyli total flavonoids in preparing medicament for treating uveitis 2026-05-26 CN claimed
CN-122074495-A Application of methyl ferulate in preventing and controlling anthracnose of apples 2026-05-26 CN claimed
CN-122075603-A Preparation method and application of fermented pummelo peel with lung function improving and lung cell repairing functions 2026-05-26 CN claimed
CN-122080438-A Graded utilization method for total components of arundo donax guided by broken fibers in segments 2026-05-26 CN claimed
CN-122074658-A Polygonatum sibiricum-based steady-state immunity enhancing functional food 2026-05-26 CN claimed
CN-122074613-A Bergamot effervescent tablet based on microencapsulation inclusion technology and preparation method thereof 2026-05-26 CN claimed
CN-122075615-A Method for extracting polyphenol and flavone from canna edulis ker powder slag, stems, leaves and roots 2026-05-26 CN claimed
EP-0151249-A2 Stabilized solutions of hydroxyl amine or salts thereof in water or alcohols, and preparation thereof BASF Aktiengesellschaft (DE) 1985-08-14 EP claimed
US-4532254-A Inhibitor of aldose reductase KAKEN PHARMACEUTICAL CO., LTD. (JP) 1985-07-30 US claimed
EP-0121489-A1 3',4',5,7-Tetrahydroxyflavone derivatives, process for their preparation and their therapeutical use CORTIAL S.A. (FR) 1984-10-10 EP claimed
US-4473484-A PHOTOISOMERIZABLE MATERIAL, PHOTOSENSITIZER, AND BY-PRODUCT INHIBITOR AGENCY OF INDUSTRIAL SCIENCE & TECHNOLOGY (JP) 1984-09-25 US claimed
EP-0118571-A1 Inhibitor of aldose reductase Kaken Pharmaceutical Co., Ltd. (JP) 1984-09-19 EP claimed
EP-0072620-A1 3-Methylflavone-8-carboxylic acid esters RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) 1983-02-23 EP claimed
EP-0052086-A1 Process for producing flavone derivatives with medicinal activity BONOMELLI S.p.A. (IT) 1982-05-19 EP claimed
EP-0019524-A1 Process for preparing flavilium derivatives, products obtained by the processus and their therapeutical application SOCIETE DE RECHERCHES INDUSTRIELLES SORI (FR) 1980-11-26 EP claimed
US-4191320-A THERMOPLASTIC RESIN, TWO AROMATIC CARBONYL SENSITIZERS OWENS-ILLINOIS, INC. (US) 1980-03-04 US claimed
US-4056665-A Composition and process OWENS-ILLINOIS, INC. (US) 1977-11-01 US claimed