SCHEMBL2404790

SCHEMBL2404790

Cc1cn([C@H]2CC(O)[C@@H](COP(=O)(O)OP(=O)(O)OP(=O)(O)S)O2)c(=O)[nH]c1=O

nearest known ligand 0.73

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
POLB P06746 2/20 0.72
POLA1 P09884 1/20 0.67
POLD1 P28340 1/20 0.67
DTYMK P23919 4/20 0.64
TYMS P04818 1/20 0.62
TK1 P04183 3/20 0.61

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6839682 0.96 POLB (0.77) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL14279191 0.94 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL21275938 0.94 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
SCHEMBL887725 0.94 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL11055949 0.94 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL77831 0.94 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL18785124 0.94 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
SCHEMBL21682516 0.94 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Deoxythymidine_Triphosphate SCHEMBL1579556 0.94 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS
Telbivudine 5'Triphosphate SCHEMBL29725270 0.94 POLB (0.78) POLBPOLA1POLD1DTYMKTYMS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11605446-B2 Methods and systems for determining haplotypes and phasing of haplotypes ILLUMINA CAMBRIDGE LIMITED (GB) 2023-03-14 US disclosed
US-20220180970-A1 METHODS AND SYSTEMS FOR DETERMINING HAPLOTYPES AND PHASING OF HAPLOTYPES ILLUMINA CAMBRIDGE LIMITED (GB) 2022-06-09 US disclosed
US-20220180969-A1 METHODS AND SYSTEMS FOR DETERMINING HAPLOTYPES AND PHASING OF HAPLOTYPES ILLUMINA CAMBRIDGE LIMITED (GB) 2022-06-09 US disclosed
US-11257568-B2 Methods and systems for determining haplotypes and phasing of haplotypes ILLUMINA CAMBRIDGE LIMITED (GB) 2022-02-22 US disclosed
US-10428363-B2 Amplification methods to minimise sequence specific bias ILLUMINA CAMBRIDGE LIMITED (GB) 2019-10-01 US disclosed
US-20180322243-A1 METHODS AND SYSTEMS FOR DETERMINING HAPLOTYPES AND PHASING OF HAPLOTYPES ILLUMINA CAMBRIDGE LIMITED (GB) 2018-11-08 US disclosed
US-9977861-B2 Methods and systems for determining haplotypes and phasing of haplotypes ILLUMINA CAMBRIDGE LIMITED (GB) 2018-05-22 US disclosed
EP-2875150-B1 METHODS AND SYSTEMS FOR DETERMINING HAPLOTYPES AND PHASING OF HAPLOTYPES ILLUMINA CAMBRIDGE LTD (GB) 2017-05-17 EP disclosed
US-20170029857-A1 AMPLIFICATION METHODS TO MINIMISE SEQUENCE SPECIFIC BIAS ILLUMINA CAMBRIDGE LIMITED (GB) 2017-02-02 US disclosed
EP-2539464-B1 AMPLIFICATION METHODS TO MINIMISE SEQUENCE SPECIFIC BIAS ILLUMINA INC (US) 2016-11-16 EP disclosed
EP-2539464-A2 AMPLIFICATION METHODS TO MINIMISE SEQUENCE SPECIFIC BIAS Illumina, Inc. (US) 2013-01-02 EP disclosed
WO-2011106368-A2 AMPLIFICATION METHODS TO MINIMISE SEQUENCE SPECIFIC BIAS ILLUMINA, INC. (US) 2011-09-01 WO disclosed
EP-1879906-A4 REVERSIBLE NUCLEOTIDE TERMINATORS AND USES THEREOF ADVANCED GENETIC ANALYSIS CORP (US) 2009-07-22 EP disclosed
EP-1879906-A2 REVERSIBLE NUCLEOTIDE TERMINATORS AND USES THEREOF AB Advanced Genetic Analysis Corporation (US) 2008-01-23 EP disclosed
WO-2006074351-A2 REVERSIBLE NUCLEOTIDE TERMINATORS AND USES THEREOF AGENCOURT PERSONAL GENOMICS (US) 2006-07-13 WO disclosed
EP-1498497-A2 Method of nucleic acid analysis by mass spectrometry Cancer Research Technology Limited (GB) 2005-01-19 EP disclosed
EP-0813609-B1 METHOD OF NUCLEIC ACID ANALYSIS CANCER REC TECH LTD (GB) 2004-10-13 EP disclosed
US-6268129-B1 MASS SPECTROMETRY OF CHARGED NUCLEIC ACID; DNA SEQUENCING IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) 2001-07-31 US disclosed
EP-0813609-A1 METHOD OF NUCLEIC ACID ANALYSIS IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) 1997-12-29 EP disclosed
WO-1996027681-A1 METHOD OF NUCLEIC ACID ANALYSIS IMPERIAL CANCER RESEARCH TECHNOLOGY LIMITED (GB) 1996-09-12 WO disclosed