Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 9/20 | 0.48 |
| ▸ | POLB | P06746 | 5/20 | 0.48 |
| ▸ | MEN1 | O00255 | 4/20 | 0.48 |
| ▸ | ESR1 | P03372 | 2/20 | 0.48 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 6/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 3/20 | 0.40 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2405147 | 0.88 | ESR1 (0.46) | KMT2APOLBMEN1ESR1ESR2 | |
| SCHEMBL2403661 | 0.87 | LMNA (0.46) | KMT2APOLBMEN1ESR1ESR2 | |
| SCHEMBL2408510 | 0.86 | HDAC6 (0.41) | KMT2APOLBMEN1MAPTKDM4E | |
| SCHEMBL20646411 | 0.85 | KMT2A (0.62) | KMT2APOLBMEN1ESR1ESR2 | |
| SCHEMBL2403746 | 0.82 | KMT2A (0.45) | KMT2APOLBMEN1ESR1ESR2 | |
| SCHEMBL2406858 | 0.82 | KMT2A (0.47) | KMT2APOLBMEN1ESR1ESR2 | |
| SCHEMBL17502684 | 0.81 | KMT2A (0.58) | KMT2APOLBMEN1ESR1ESR2 | |
| SCHEMBL2403754 | 0.81 | KMT2A (0.50) | KMT2APOLBMEN1ESR1ESR2 | |
| SCHEMBL2409256 | 0.80 | KMT2A (0.47) | KMT2APOLBMEN1ESR1ESR2 | |
| SCHEMBL2409038 | 0.79 | KMT2A (0.44) | KMT2APOLBMEN1ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3118226-A1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF Corporation (US) | 2017-01-18 | — | — | EP | claimed |
| EP-2782938-B1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF CORP (US) | 2016-08-31 | — | — | EP | claimed |
| US-9284392-B2 | Mixed internal donor structures for 1-olefin polymerization catalysts | BASF CORPORATION (US) | 2016-03-15 | — | — | US | claimed |
| EP-2970521-A1 | MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS | BASF Corporation (US) | 2016-01-20 | — | — | EP | claimed |
| EP-2782938-A1 | HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME | BASF Corporation (US) | 2014-10-01 | — | — | EP | claimed |
| WO-2014149628-A1 | MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS | BASF CORPORATION (US) | 2014-09-25 | — | — | WO | claimed |
| WO-2013077837-A1 | HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME | BASF CORPORATION (US) | 2013-05-30 | — | — | WO | claimed |
| US-8318626-B2 | Internal and external donor compounds for olefin polymerization catalysts III | BASF CORPORATION (US) | 2012-11-27 | — | — | US | claimed |
| US-8227370-B2 | High activity catalyst component for olefin polymerization and method of using the same | BASF CORPORATION (US) | 2012-07-24 | — | — | US | claimed |
| US-20120116031-A1 | High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same | BASF CORPORATION (US) | 2012-05-10 | — | — | US | claimed |
| US-20110213106-A1 | Internal and External Donor Compounds for Olefin Polymerization Catalysts III | BASF CATALYSTS LLC (US) | 2011-09-01 | — | — | US | claimed |
| EP-3118226-A1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF Corporation (US) | 2017-01-18 | — | — | EP | disclosed |
| EP-2782938-B1 | HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION | BASF CORP (US) | 2016-08-31 | — | — | EP | disclosed |
| US-9284392-B2 | Mixed internal donor structures for 1-olefin polymerization catalysts | BASF CORPORATION (US) | 2016-03-15 | — | — | US | disclosed |
| EP-2970521-A1 | MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS | BASF Corporation (US) | 2016-01-20 | — | — | EP | disclosed |
| WO-2013077837-A1 | HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME | BASF CORPORATION (US) | 2013-05-30 | — | — | WO | disclosed |
| US-8318626-B2 | Internal and external donor compounds for olefin polymerization catalysts III | BASF CORPORATION (US) | 2012-11-27 | — | — | US | disclosed |
| US-8227370-B2 | High activity catalyst component for olefin polymerization and method of using the same | BASF CORPORATION (US) | 2012-07-24 | — | — | US | disclosed |
| US-20120116031-A1 | High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same | BASF CORPORATION (US) | 2012-05-10 | — | — | US | disclosed |
| US-20110213106-A1 | Internal and External Donor Compounds for Olefin Polymerization Catalysts III | BASF CATALYSTS LLC (US) | 2011-09-01 | — | — | US | disclosed |