SCHEMBL2409256

SCHEMBL2409256

Cc1ccccc1C(=O)Oc1cccc2cccc(OC(=O)C3=CCCCC3)c12

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.47
MEN1 O00255 3/20 0.47
ESR1 P03372 1/20 0.47
ESR2 Q92731 1/20 0.47
PKM P14618 1/20 0.43
NPSR1 Q6W5P4 2/20 0.41
CYP3A4 P08684 1/20 0.41
CYP2C9 P11712 1/20 0.41
CYP2C19 P33261 1/20 0.41
MAPT P10636 3/20 0.39
KDM4E B2RXH2 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
POLB P06746 2/20 0.39
GAA P10253 1/20 0.39
NPC1 O15118 4/20 0.38
RAB9A P51151 3/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2408510 0.87 HDAC6 (0.41) KMT2AMEN1MAPTKDM4ETDP1
SCHEMBL20646377 0.84 KMT2A (0.61) KMT2AMEN1ESR1ESR2PKM
SCHEMBL2403661 0.83 LMNA (0.46) KMT2AMEN1ESR1ESR2NPSR1
SCHEMBL18035746 0.82 MYC (0.40) KMT2AMEN1ESR1ESR2CYP2C9
SCHEMBL2405147 0.82 ESR1 (0.46) KMT2AMEN1ESR1ESR2MAPT
SCHEMBL2404706 0.82 KMT2A (0.46) KMT2AMEN1ESR1ESR2PKM
SCHEMBL2402673 0.82 KMT2A (0.44) KMT2AMEN1ESR1ESR2PKM
SCHEMBL2403973 0.81 KMT2A (0.49) KMT2AMEN1ESR1ESR2PKM
SCHEMBL2405002 0.80 KMT2A (0.48) KMT2AMEN1ESR1ESR2CYP3A4
SCHEMBL16554699 0.80 HSD17B10 (0.44) KMT2AESR1CYP2C9MAPTKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP claimed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP claimed
US-9284392-B2 Mixed internal donor structures for 1-olefin polymerization catalysts BASF CORPORATION (US) 2016-03-15 US claimed
EP-2970521-A1 MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS BASF Corporation (US) 2016-01-20 EP claimed
EP-2782938-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF Corporation (US) 2014-10-01 EP claimed
WO-2014149628-A1 MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS BASF CORPORATION (US) 2014-09-25 WO claimed
US-20140275452-A1 MIXED INTERNAL DONOR STRUCTURES FOR 1-OLEFIN POLYMERIZATION CATALYSTS BASF CATALYSTS LLC (US) 2014-09-18 US claimed
WO-2013077837-A1 HIGH ACTIVITY CATALYST COMPONENT FOR OLEFIN POLYMERIZATION AND METHOD OF USING THE SAME BASF CORPORATION (US) 2013-05-30 WO claimed
US-8318626-B2 Internal and external donor compounds for olefin polymerization catalysts III BASF CORPORATION (US) 2012-11-27 US claimed
WO-2012118510-A1 INTERNAL AND EXTERNAL DONOR COMPOUNDS FOR OLEFIN POLYMERIZATION CATALYSTS III BASF CORPORATION (US) 2012-09-07 WO claimed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US claimed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US claimed
US-20110213106-A1 Internal and External Donor Compounds for Olefin Polymerization Catalysts III BASF CATALYSTS LLC (US) 2011-09-01 US claimed
EP-3118226-A1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF Corporation (US) 2017-01-18 EP disclosed
EP-2782938-B1 HIGH ACTIVITY CATALYST FOR OLEFIN POLYMERIZATION BASF CORP (US) 2016-08-31 EP disclosed
US-9284392-B2 Mixed internal donor structures for 1-olefin polymerization catalysts BASF CORPORATION (US) 2016-03-15 US disclosed
US-8318626-B2 Internal and external donor compounds for olefin polymerization catalysts III BASF CORPORATION (US) 2012-11-27 US disclosed
US-8227370-B2 High activity catalyst component for olefin polymerization and method of using the same BASF CORPORATION (US) 2012-07-24 US disclosed
US-20120116031-A1 High Activity Catalyst Component for Olefin Polymerization and Method of Using the Same BASF CORPORATION (US) 2012-05-10 US disclosed
US-20110213106-A1 Internal and External Donor Compounds for Olefin Polymerization Catalysts III BASF CATALYSTS LLC (US) 2011-09-01 US disclosed