⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30824460 | 0.82 | — | — | |
| SCHEMBL1409240 | 0.82 | — | — | |
| SCHEMBL6231124 | 0.79 | — | — | |
| SCHEMBL23419456 | 0.77 | TSHR (0.30) | — | |
| SCHEMBL23117842 | 0.74 | — | — | |
| SCHEMBL13292084 | 0.74 | — | — | |
| SCHEMBL252367 | 0.73 | TSHR (0.30) | — | |
| SCHEMBL7262903 | 0.73 | TSHR (0.30) | — | |
| SCHEMBL7858703 | 0.73 | TSHR (0.30) | — | |
| Hydrochloric Acid SCHEMBL25380883 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1165569-B1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | AGILENT TECHNOLOGIES INC (US) | 2005-08-10 | — | — | EP | claimed |
| EP-1165569-A1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | Agilent Technologies, Inc. (US) | 2002-01-02 | — | — | EP | claimed |
| WO-2000056740-A1 | BORONIC ACID CONTAINING REAGENTS AND OLIGONUCLEOTIDES | PROLINX, INC. (US) | 2000-09-28 | — | — | WO | claimed |
| US-6031117-A | Boronic acid containing phosphoramidite reagents | PROLINX INCORPORATED (US) | 2000-02-29 | — | — | US | claimed |
| US-5869644-A | Synthesis of diverse and useful collections of oligonucleotidies | THE JOHNS HOPKINS UNIVERSITY (US) | 1999-02-09 | — | — | US | claimed |
| US-8026349-B2 | Polynucleotide synthesis labeling chemistry | DHARMACON, INC. (US) | 2011-09-27 | — | — | US | disclosed |
| US-7687618-B2 | reaction of an oligonucleotide having a labile protecting group bound to a terminal hydroxy group, and a labeling compound; nucleophilic substitution reaction; lower reaction times and yields are advantageous for the user because they permit a high throughput with low technical requirements | NIMBLEGEN SYSTEMS GMBH (DE) | 2010-03-30 | — | — | US | disclosed |
| WO-2009143369-A2 | METHOD OF PREPARING NUCLEOSIDES AND ANALOGS THEREOF WITHOUT USING CHROMATOGRAPHY | ISIS PHARMACEUTICALS, INC. (US) | 2009-11-26 | — | — | WO | disclosed |
| EP-0638089-B2 | SYNTHESIS OF DIVERSE AND USEFUL COLLECTIONS OF OLIGONUCLEOTIDES | UNIV JOHNS HOPKINS (US) | 2008-03-05 | — | — | EP | disclosed |
| US-20080009612-A1 | Novel Polynucleotide Synthesis Labeling Chemistry | DHARMACON, INC. | 2008-01-10 | — | — | US | disclosed |
| EP-1788875-A2 | NOVEL POLYNUCLEOTIDE SYNTHESIS LABELING CHEMISTRY | Dharmacon, Inc. (US) | 2007-05-30 | — | — | EP | disclosed |
| US-20060122382-A1 | Method of manufacturing labelled oligonucleotide conjugates | NIMBLEGENSYSTEMS GMBH (DE) | 2006-06-08 | — | — | US | disclosed |
| US-5393878-A | Pyrimidine nucleosides having cyclopentafuran skeleton | CIBA-GEIGY CORPORATION (US) | 1995-02-28 | — | — | US | disclosed |
| EP-0638089-A1 | SYNTHESIS OF DIVERSE AND USEFUL COLLECTIONS OF OLIGONUCLEOTIDES | THE JOHNS HOPKINS UNIVERSITY (US) | 1995-02-15 | — | — | EP | disclosed |
| EP-0633890-A1 | SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS | ZENECA LIMITED (GB) | 1995-01-18 | — | — | EP | disclosed |
| US-5319080-A | Antiviral agents | CIBA-GEIGY CORPORATION (US) | 1994-06-07 | — | — | US | disclosed |
| WO-1993021203-A1 | SYNTHESIS OF DIVERSE AND USEFUL COLLECTIONS OF OLIGONUCLEOTIDES | THE JOHNS HOPKINS UNIVERSITY (US) | 1993-10-28 | — | — | WO | disclosed |
| WO-1993020091-A1 | SUPPORT FOR OLIGONUCLEOTIDE SYNTHESIS | ZENECA LIMITED (GB) | 1993-10-14 | — | — | WO | disclosed |
| EP-0451141-A1 | IMMOBILIZED SEQUENCE-SPECIFIC PROBES | F. HOFFMANN-LA ROCHE AG (CH) | 1991-10-16 | — | — | EP | disclosed |
| WO-1989011548-A1 | IMMOBILIZED SEQUENCE-SPECIFIC PROBES | CETUS CORPORATION (US) | 1989-11-30 | — | — | WO | disclosed |