⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1409240 | 0.82 | — | — | |
| SCHEMBL30824460 | 0.82 | — | — | |
| SCHEMBL2405006 | 0.79 | — | — | |
| SCHEMBL10590957 | 0.77 | TSHR (0.30) | — | |
| SCHEMBL16144665 | 0.74 | — | — | |
| SCHEMBL22415309 | 0.74 | — | — | |
| SCHEMBL285592 | 0.73 | TSHR (0.30) | — | |
| SCHEMBL8741526 | 0.73 | TSHR (0.30) | — | |
| Hydrochloric Acid SCHEMBL2951043 | 0.71 | — | — | |
| SCHEMBL10305780 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2487180-B1 | NOVEL ARTIFICIAL FLUORESCENT BASES | RIKEN (JP) | 2014-12-03 | — | — | EP | disclosed |
| US-8895712-B2 | Artificial base pair capable of forming specific base pair | RIKEN (JP) | 2014-11-25 | — | — | US | disclosed |
| US-8673885-B1 | Compounds for the protection of sulfur containing linkers in nucleic acid synthesis | DUFF ROBERT (US) | 2014-03-18 | — | — | US | disclosed |
| US-20120231462-A1 | ARTIFICIAL BASE PAIR CAPABLE OF FORMING SPECIFIC BASE PAIR | TAGCYX BIOTECHNOLOGIES (JP) | 2012-09-13 | — | — | US | disclosed |
| EP-2487180-A1 | NOVEL ARTIFICIAL FLUORESCENT BASES | Riken (JP) | 2012-08-15 | — | — | EP | disclosed |
| EP-2487181-A1 | ARTIFICIAL BASE PAIR CAPABLE OF FORMING SPECIFIC BASE PAIR | Riken (JP) | 2012-08-15 | — | — | EP | disclosed |
| EP-1602725-A2 | Abasic-nucleotide containing enzymatic nucleic acid | RIBOZYME PHARMACEUTICALS, INC. (US) | 2005-12-07 | — | — | EP | disclosed |
| US-20050147973-A1 | Immobilized probes | GE HEALTHCARE UK LIMITED (GB) | 2005-07-07 | — | — | US | disclosed |
| EP-1520038-A2 | DETECTION OF CIRCULARIZED IMMOBILIZED NUCLEIC ACID PROBES | Amersham Biosciences UK Limited (GB) | 2005-04-06 | — | — | EP | disclosed |
| US-6849726-B2 | Non-nucleotide containing RNA | SIRNA THERAPEUTICS, INC. (US) | 2005-02-01 | — | — | US | disclosed |
| US-6555668-B2 | Comprising a non-nucleotide in a single-stranded region; hammerhead ribozyme having a non-nucleotide in the catalytic core; synthesis of abasic ribonucleoside mimetics | RIBOZYME PHARMACEUTICALS, INC. | 2003-04-29 | — | — | US | disclosed |
| US-20020193579-A1 | Non-nucleotide containing enzymatic nucleic acid | RIBOZYME PHARMACEUTICALS, INC. | 2002-12-19 | — | — | US | disclosed |
| EP-1253199-A1 | Abasic moieties containing enzymatic nucleic acids | RIBOZYME PHARMACEUTICALS, INC. (US) | 2002-10-30 | — | — | EP | disclosed |
| US-6362323-B1 | HAVING ACTIVITY TO CLEAVE AN RNA OR DNA MOLECULE | RIBOZYME PHARMACEUTICALS, INC. | 2002-03-26 | — | — | US | disclosed |
| US-6117657-A | ENZYMATIC NUCLEIC ACID MOLECULE CONTAINING ONE OR MORE NON-NUCLEOTIDE MIMETICS, AND HAVING ACTIVITY TO CLEAVE AN RNA OR DNA MOLECULE | RIBOZYME PHARMACEUTICALS, INC. (US) | 2000-09-12 | — | — | US | disclosed |
| US-6008398-A | Non-nucleotide phosphorus ester oligomers | GENZYME CORPORATION (US) | 1999-12-28 | — | — | US | disclosed |
| EP-0880532-A4 | NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS | PHARMAGENICS INC (US) | 1999-06-09 | — | — | EP | disclosed |
| US-5891683-A | Non-nucleotide containing enzymatic nucleic acid | RIBOZYME PHARMACEUTICALS, INC. (US) | 1999-04-06 | — | — | US | disclosed |
| EP-0880532-A1 | NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS | PHARMAGENICS, INC. (US) | 1998-12-02 | — | — | EP | disclosed |
| WO-1997028168-A1 | NON-NUCLEOTIDE PHOSPHOROUS ESTER OLIGOMERS | PHARMAGENICS, INC. (US) | 1997-08-07 | — | — | WO | disclosed |