SCHEMBL240503

SCHEMBL240503

C[C@H](CN)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TAAR1 Q96RJ0 5/20 1.00
HTR2A P28223 2/20 0.59
AOC3 Q16853 2/20 0.58
TRPA1 O75762 4/20 0.50
RIPK1 Q13546 1/20 0.50
CHRNB2 P17787 1/20 0.48
CHRNA4 P43681 1/20 0.48
HRH1 P35367 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2107 1.00 TAAR1 (1.00) TAAR1HTR2AAOC3TRPA1RIPK1
SCHEMBL238388 1.00 TAAR1 (1.00) TAAR1HTR2AAOC3TRPA1RIPK1
Bromide SCHEMBL29883460 0.97 TAAR1 (0.95) TAAR1HTR2AAOC3TRPA1RIPK1
Bromide SCHEMBL28358414 0.97 TAAR1 (0.95) TAAR1HTR2AAOC3TRPA1RIPK1
Hydrochloric Acid SCHEMBL337907 0.97 TAAR1 (0.95) TAAR1HTR2AAOC3TRPA1RIPK1
SCHEMBL1930994 0.91 TAAR1 (0.83) TAAR1HTR2AAOC3TRPA1RIPK1
SCHEMBL28569127 0.91 TAAR1 (0.83) TAAR1HTR2AAOC3TRPA1RIPK1
Bicarbonate SCHEMBL9490583 0.91 TAAR1 (0.83) TAAR1HTR2AAOC3TRPA1
SCHEMBL28569125 0.91 TAAR1 (0.83) TAAR1HTR2AAOC3TRPA1RIPK1
Ammonia Solution, Strong SCHEMBL8416958 0.87 TAAR1 (0.76) TAAR1HTR2AAOC3TRPA1RIPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 427 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118946165-A Interface interaction spin-photon conversion body heterostructure and preparation method 武汉大学 2024-11-12 CN claimed
CN-117617501-A Extraction process of lime peel 江西省林业科学院 2024-03-01 CN claimed
CN-111362809-B Chiral perovskite nanosheet, and preparation method and application thereof 国家纳米科学中心 2023-03-31 CN claimed
CN-111362809-A Chiral perovskite nanosheet, and preparation method and application thereof 国家纳米科学中心 2020-07-03 CN claimed
US-9833768-B2 Affinity reagents for protein purification IMPOSSIBLE FOODS INC. (US) 2017-12-05 US claimed
US-20170320041-A1 AFFINITY REAGENTS FOR PROTEIN PURIFICATION IMPOSSIBLE FOODS INC. 2017-11-09 US claimed
US-9737875-B2 Affinity reagents for protein purification IMPOSSIBLE FOODS INC. (US) 2017-08-22 US claimed
CN-104620104-B Affinity Reagents for Protein Purification 非凡食品有限公司 2017-03-01 CN claimed
US-8487131-B2 Optically pure apogossypol derivative as pan-active inhibitor of anti-apoptotic B-cell lymphoma/leukemia-2 (BCL-2) SANFORD-BURNHAM MEDICAL RESEARCH INSTITUTE (US) 2013-07-16 US claimed
CN-1558898-A Antiviral agent ��Ұ����ҩ��ʽ���� 2004-12-29 CN claimed
EP-1422218-A1 ANTIVIRAL AGENT SHIONOGI & CO., LTD. (JP) 2004-05-26 EP claimed
US-20250368633-A1 AZEPINE FUSED RING COMPOUND AS RIPK1 INHIBITOR AND USE THEREOF ARTIVILA BIOPHARMA (CN) 2025-12-04 US disclosed
CN-120967513-A One-dimensional bismuth-based chiral perovskite crystal and preparation method and application thereof 河南省科学院半导体研究所 2025-11-18 CN disclosed
EP-4582414-A1 AZEPINE FUSED RING COMPOUND AS RIPK1 INHIBITOR AND USE THEREOF Artivila Biopharma (CN) 2025-07-09 EP disclosed
CN-118946165-A Interface interaction spin-photon conversion body heterostructure and preparation method 武汉大学 2024-11-12 CN disclosed
US-5034381-A Antagonist CIBA-GEIGY CORPORATION (US) 1991-07-23 US disclosed
EP-0277917-A2 Certain adenosine 5'-carboxamide derivatives CIBA-GEIGY AG (CH) 1988-08-10 EP disclosed
US-4698329-A HYPOTENSIVE AGENTS SANKYO COMPANY, LIMITED (JP) 1987-10-06 US disclosed
EP-0152255-A2 New renin-inhibitory peptides and their use SANKYO COMPANY LIMITED (JP) 1985-08-21 EP disclosed
EP-0006735-A1 Secondary amines, their preparation, pharmaceutical compositions containing them and their use BEECHAM GROUP PLC (GB) 1980-01-09 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250368633-A1 AZEPINE FUSED RING COMPOUND AS RIPK1 INHIBITOR AND USE THEREOF RIPK1, RIPK2, RIPK4 TAAR1 4751/4885HTR2A 3710/4885AOC3 4591/4885
US-20170320041-A1 AFFINITY REAGENTS FOR PROTEIN PURIFICATION RAB5IF, MRPL21, RPS27A TAAR1 4419/4885HTR2A 4416/4885AOC3 4516/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.