Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | TNFSF10 | P50591 | 1/20 | 0.47 |
| ▸ | XBP1 | P17861 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | XDH | P47989 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MMP9 | P14780 | 1/20 | 0.42 |
| ▸ | MMP8 | P22894 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | APP | P05067 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9080021 | 0.89 | TNFSF10 (0.45) | NPC1RAB9ATNFSF10XBP1HTT | |
| SCHEMBL9871665 | 0.84 | KMT2A (0.56) | NPC1RAB9AHTTNPSR1XDH | |
| SCHEMBL29769219 | 0.81 | XDH (0.58) | NPC1RAB9ATNFSF10XBP1HTT | |
| SCHEMBL8412982 | 0.81 | NPC1 (0.38) | NPC1RAB9AHTTMAPTMEN1 | |
| SCHEMBL9871669 | 0.80 | EIF4E (0.43) | NPC1RAB9AXBP1HTTNPSR1 | |
| SCHEMBL1409329 | 0.77 | NPC1 (0.50) | NPC1RAB9ATNFSF10XBP1HTT | |
| SCHEMBL2117163 | 0.75 | NPC1 (0.49) | NPC1RAB9ATNFSF10XBP1HTT | |
| SCHEMBL629172 | 0.75 | MAPT (0.53) | NPC1RAB9ATNFSF10XBP1HTT | |
| SCHEMBL11166733 | 0.74 | MAPT (0.57) | NPC1RAB9ATNFSF10XBP1HTT | |
| SCHEMBL22604036 | 0.74 | MAPK1 (0.62) | NPC1RAB9AXBP1HTTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2356182-B1 | RADIATION CURABLE COATING MATERIALS | BASF SE (DE) | 2015-05-06 | — | — | EP | disclosed |
| CN-102216400-B | Radiation curable coating materials | BASF SE | 2013-12-18 | — | — | CN | disclosed |
| US-20130299736-A1 | RADIATION-CURABLE COATING MATERIALS | BASE SE (DE) | 2013-11-14 | — | — | US | disclosed |
| US-20110230617-A1 | RADIATION-CURABLE COATING MATERIALS | BASF SE (DE) | 2011-09-22 | — | — | US | disclosed |
| US-20100126386-A1 | RADIATION-CURABLE COATING SUBSTANCES | BASF AKTIENGESELLSCHAFT (DE) | 2010-05-27 | — | — | US | disclosed |
| US-20100016465-A1 | Composite Material Comprising A Water-Or Acid-Releasing Agent | DENTOFIT A/S (DK) | 2010-01-21 | — | — | US | disclosed |
| US-20100016465-A1 | Composite Material Comprising A Water-Or Acid-Releasing Agent | DENTOFIT A/S (DK) | 2010-01-21 | — | — | US | disclosed |
| US-6110987-A | CURED PRODUCTS HAVING AN EXCELLENT APPEARANCE WITHOUT COLORING CAUSED BY POLYMERIZATION INITIATOR | SHOWA DENKO K.K. (JP) | 2000-08-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100016465-A1 | Composite Material Comprising A Water-Or Acid-Releasing Agent | PLA2G2C, SMARCA1, VMA21 | NPC1 4633/4885RAB9A 1007/4885TNFSF10 2082/4885 |
| US-20110230617-A1 | RADIATION-CURABLE COATING MATERIALS | RAD51, MGMT, RAD54L | NPC1 1213/4885RAB9A 1455/4885TNFSF10 2893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.