Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.32 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.32 |
| ▸ | CDK1 | P06493 | 1/20 | 0.32 |
| ▸ | CDK4 | P11802 | 1/20 | 0.32 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.32 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.32 |
| ▸ | CCND1 | P24385 | 1/20 | 0.32 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.32 |
| ▸ | CDK2 | P24941 | 1/20 | 0.32 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.32 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.31 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL80044 | 0.91 | NPC1 (0.52) | NPC1RAB9AMEN1KMT2AADORA3 | |
| SCHEMBL125466 | 0.89 | MEN1 (0.44) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL126470 | 0.89 | RAB9A (0.37) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL80269 | 0.89 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL130297 | 0.89 | NR1H4 (0.39) | NPC1RAB9AMEN1KMT2AL3MBTL1 | |
| SCHEMBL8607879 | 0.89 | MEN1 (0.48) | NPC1RAB9AMEN1KMT2APOLB | |
| SCHEMBL306970 | 0.89 | MEN1 (0.46) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL125517 | 0.89 | NPC1 (0.50) | NPC1RAB9AMEN1KMT2AADORA3 | |
| SCHEMBL22129836 | 0.89 | NPC1 (0.41) | NPC1RAB9AMEN1KMT2AHTT | |
| SCHEMBL80527 | 0.88 | MEN1 (0.47) | NPC1RAB9AMEN1KMT2AHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0519299-B1 | Positive-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | CLARIANT GMBH (DE) | 1999-08-11 | — | — | EP | disclosed |
| US-5364734-A | Sulfonated triazines | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-11-15 | — | — | US | disclosed |
| EP-0519298-A1 | Radiation-sensitive sulfonic acid esters and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-23 | — | — | EP | disclosed |
| EP-0519299-A1 | Positive-working radiation-sensitive composition and radiation-sensitive recording material produced therewith | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-12-23 | — | — | EP | disclosed |