Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.48 |
| ▸ | HTT | P42858 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | HAO1 | Q9UJM8 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24051983 | 0.85 | KMT2A (0.51) | KMT2AHTTALDH1A1KDM4ELMNA | |
| SCHEMBL25754226 | 0.85 | KMT2A (0.48) | KMT2AHTTALDH1A1KDM4ELMNA | |
| SCHEMBL25753329 | 0.83 | KMT2A (0.49) | KMT2AHTTALDH1A1KDM4ELMNA | |
| SCHEMBL13105958 | 0.75 | HTT (0.50) | HTTALDH1A1PIN1RAB9ATAS1R3 | |
| SCHEMBL31262315 | 0.73 | HTT (0.49) | KMT2AHTTALDH1A1PIN1RAB9A | |
| SCHEMBL2448483 | 0.73 | HTT (0.49) | KMT2AHTTALDH1A1PIN1RAB9A | |
| SCHEMBL11599097 | 0.72 | ALDH1A1 (0.49) | KMT2AHTTALDH1A1RAB9AMEN1 | |
| SCHEMBL27261538 | 0.72 | HTT (0.51) | KMT2AHTTALDH1A1PIN1MEN1 | |
| SCHEMBL769134 | 0.72 | KMT2A (0.51) | KMT2AHTTALDH1A1PIN1MEN1 | |
| SCHEMBL3412231 | 0.72 | PRMT5 (0.52) | KMT2AHTTALDH1A1RAB9AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022099159-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2022-05-12 | — | — | WO | disclosed |
| WO-2021234459-A2 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |
| WO-2021237223-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |