Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RIPK1 | Q13546 | 5/20 | 0.35 |
| ▸ | ACVRL1 | P37023 | 4/20 | 0.34 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23813354 | 1.00 | RIPK1 (0.35) | RIPK1ACVRL1MAP4K4 | |
| SCHEMBL21283655 | 0.88 | RIPK1 (0.35) | RIPK1ACVRL1 | |
| SCHEMBL19223085 | 0.87 | RIPK1 (0.32) | RIPK1MAP4K4 | |
| SCHEMBL22143019 | 0.85 | RIPK1 (0.32) | RIPK1 | |
| SCHEMBL27284023 | 0.83 | RIPK1 (0.36) | RIPK1ACVRL1 | |
| SCHEMBL24982190 | 0.82 | RIPK1 (0.35) | RIPK1ACVRL1MAP4K4 | |
| SCHEMBL25008851 | 0.82 | RIPK1 (0.35) | RIPK1ACVRL1MAP4K4 | |
| SCHEMBL24982607 | 0.82 | RIPK1 (0.35) | RIPK1ACVRL1MAP4K4 | |
| SCHEMBL24982606 | 0.82 | RIPK1 (0.35) | RIPK1ACVRL1MAP4K4 | |
| SCHEMBL18214622 | 0.80 | ACVRL1 (0.34) | RIPK1ACVRL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3212175-B1 | METHODS FOR THE PREPARATION OF RIBOSIDES | GILEAD SCIENCES INC (US) | 2021-11-24 | — | — | EP | disclosed |