⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17712280 | 0.81 | — | — | |
| SCHEMBL12243172 | 0.78 | PRMT5 (0.30) | — | |
| SCHEMBL25218817 | 0.76 | TMPRSS2 (0.46) | — | |
| SCHEMBL24789791 | 0.75 | PI4KA (0.30) | — | |
| SCHEMBL20380379 | 0.75 | — | — | |
| SCHEMBL17106728 | 0.75 | DOT1L (0.33) | — | |
| SCHEMBL23822775 | 0.74 | TNK2 (0.35) | — | |
| SCHEMBL18666953 | 0.74 | TNK2 (0.35) | — | |
| SCHEMBL13667812 | 0.74 | TNK2 (0.35) | — | |
| SCHEMBL24790992 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3212175-B1 | METHODS FOR THE PREPARATION OF RIBOSIDES | GILEAD SCIENCES INC (US) | 2021-11-24 | — | — | EP | disclosed |