SCHEMBL17712280

SCHEMBL17712280

CC(C)(C)[Si](C)(C)OC[C@H]1OC(O)(c2ccc3c(N)ncnn23)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]1O[Si](C)(C)C(C)(C)C

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29937929 0.89 — —
SCHEMBL25273133 0.86 TMPRSS2 (0.32) —
SCHEMBL25220869 0.84 — —
SCHEMBL17719368 0.83 POLRMT (0.31) —
SCHEMBL17719247 0.83 POLRMT (0.31) —
SCHEMBL12243172 0.82 PRMT5 (0.30) —
SCHEMBL24058395 0.81 — —
SCHEMBL12243173 0.78 P2RX3 (0.30) —
SCHEMBL29813386 0.78 TMPRSS2 (0.41) —
SCHEMBL17712314 0.78 TMPRSS2 (0.41) —

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4591935-A2 METHODS FOR THE PREPARATION OF RIBOSIDES Gilead Sciences, Inc. (US) 2025-07-30 — — EP disclosed
EP-4588928-A2 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS Gilead Sciences, Inc. (US) 2025-07-23 — — EP disclosed
EP-4036099-B1 METHODS FOR THE PREPARATION OF RIBOSIDES GILEAD SCIENCES INC (US) 2025-03-19 — — EP disclosed
US-20220354873-A1 METHODS FOR THE PREPARATION OF RIBOSIDES GILEAD SCIENCES, INC. 2022-11-10 — — US disclosed
EP-4036099-A1 METHODS FOR THE PREPARATION OF RIBOSIDES Gilead Sciences, Inc. (US) 2022-08-03 — — EP disclosed
US-11344565-B2 Methods for the preparation of ribosides GILEAD SCIENCES, INC. (US) 2022-05-31 — — US disclosed
US-11266666-B2 Methods for treating Filoviridae virus infections GILEAD SCIENCES, INC. (US) 2022-03-08 — — US disclosed
EP-3212175-B1 METHODS FOR THE PREPARATION OF RIBOSIDES GILEAD SCIENCES INC (US) 2021-11-24 — — EP disclosed
US-20210052613-A1 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES, INC. 2021-02-25 — — US disclosed
EP-3695844-A1 METHODS FOR TREATING NIPAH VIRUS INFECTIONS Gilead Sciences, Inc. (US) 2020-08-19 — — EP disclosed
EP-3366295-A1 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS Gilead Sciences, Inc. (US) 2018-08-29 — — EP disclosed
EP-3212174-B1 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES INC (US) 2018-05-16 — — EP disclosed
US-9949994-B2 Methods for treating Filoviridae virus infections GILEAD SCIENCES, INC. (US) 2018-04-24 — — US disclosed
EP-3212175-A1 METHODS FOR THE PREPARATION OF RIBOSIDES Gilead Sciences, Inc. (US) 2017-09-06 — — EP disclosed
US-9724360-B2 Methods for treating Filoviridae virus infections GILEAD SCIENCES, INC. (US) 2017-08-08 — — US disclosed
US-20160361330-A1 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES, INC. 2016-12-15 — — US disclosed
WO-2016069825-A1 METHODS FOR THE PREPARATION OF RIBOSIDES GILEAD SCIENCES, INC. (US) 2016-05-06 — — WO disclosed
WO-2016069827-A1 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES, INC. (US) 2016-05-06 — — WO disclosed
US-20160122356-A1 METHODS FOR THE PREPARATION OF RIBOSIDES GILEAD SCIENCES, INC. 2016-05-05 — — US disclosed
US-20160122374-A1 METHODS FOR TREATING FILOVIRIDAE VIRUS INFECTIONS GILEAD SCIENCES, INC. 2016-05-05 — — US disclosed
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