Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | VSIR | Q9H7M9 | 2/20 | 0.34 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.34 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 4/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 4/20 | 0.33 |
| ▸ | TPSAB1 | Q15661 | 4/20 | 0.33 |
| ▸ | GSR | P00390 | 1/20 | 0.31 |
| ▸ | MMP2 | P08253 | 1/20 | 0.31 |
| ▸ | MMP9 | P14780 | 1/20 | 0.31 |
| ▸ | CA1 | P00915 | 1/20 | 0.31 |
| ▸ | CA2 | P00918 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24058460 | 1.00 | FOLH1 (0.38) | FOLH1VSIRCD274CPB2PRSS1 | |
| SCHEMBL24595229 | 1.00 | FOLH1 (0.38) | FOLH1VSIRCD274CPB2PRSS1 | |
| SCHEMBL24595303 | 0.99 | FOLH1 (0.38) | FOLH1VSIRCD274CPB2PRSS1 | |
| SCHEMBL24058854 | 0.94 | FOLH1 (0.45) | FOLH1CPB2PRSS1PRSS2PRSS3 | |
| SCHEMBL24058650 | 0.92 | FOLH1 (0.43) | FOLH1VSIRCD274CPB2PRSS1 | |
| SCHEMBL24058693 | 0.92 | FOLH1 (0.43) | FOLH1VSIRCD274CPB2PRSS1 | |
| SCHEMBL24058562 | 0.89 | FOLH1 (0.33) | FOLH1VSIRCD274CPB2PRSS1 | |
| SCHEMBL20057150 | 0.89 | VSIR (0.36) | VSIRCD274MAPT | |
| SCHEMBL24595363 | 0.89 | ALDH1A1 (0.41) | FOLH1CPB2MAPT | |
| SCHEMBL24058491 | 0.89 | ALDH1A1 (0.41) | FOLH1CPB2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4023645-A1 | 1,2,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | Aurigene Discovery Technologies Limited (IN) | 2022-07-06 | — | — | EP | disclosed |
| EP-3267984-B1 | 1,2,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2021-11-24 | — | — | EP | disclosed |