Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | LIPE | Q05469 | 1/20 | 0.34 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PREP | P48147 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.31 |
| ▸ | PDE9A | O76083 | 1/20 | 0.31 |
| ▸ | PDE1B | Q01064 | 1/20 | 0.31 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.31 |
| ▸ | SCD5 | Q86SK9 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24058502 | 0.88 | ACE (0.37) | HSD17B10MAPTCYP3A4CYP2C9PKM | |
| SCHEMBL24058544 | 0.88 | ACE (0.37) | HSD17B10MAPTCYP3A4CYP2C9PKM | |
| SCHEMBL24058760 | 0.75 | REN (0.39) | HSD17B10MAPTCYP3A4CYP2C9PKM | |
| SCHEMBL25476856 | 0.71 | ACE (0.37) | ALDH1A1DPP7DPP4MEN1KMT2A | |
| SCHEMBL25476847 | 0.71 | F2 (0.36) | ALDH1A1MEN1KMT2APOLBCYP3A4 | |
| SCHEMBL25476852 | 0.71 | CYP3A4 (0.46) | ALDH1A1MEN1KMT2APOLBCYP3A4 | |
| SCHEMBL21168328 | 0.71 | ACE (0.43) | ALDH1A1DPP7DPP4KMT2ACYP3A4 | |
| SCHEMBL21168279 | 0.71 | ACE (0.43) | ALDH1A1DPP7DPP4KMT2ACYP3A4 | |
| SCHEMBL25476858 | 0.71 | DPP4 (0.34) | DPP7DPP4MEN1KMT2ATP53 | |
| SCHEMBL21168269 | 0.71 | LTA4H (0.47) | ALDH1A1MEN1KMT2APOLBCYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3267984-B1 | 1,2,4-OXADIAZOLE AND THIADIAZOLE COMPOUNDS AS IMMUNOMODULATORS | AURIGENE DISCOVERY TECH LTD (IN) | 2021-11-24 | — | — | EP | disclosed |