Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 6/20 | 0.50 |
| ▸ | TOP2A | P11388 | 4/20 | 0.48 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.48 |
| ▸ | DHFR | P00374 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22020924 | 1.00 | TK1 (0.50) | TK1TOP2ARNASE1DHFR | |
| SCHEMBL24233273 | 1.00 | TK1 (0.50) | TK1TOP2ARNASE1DHFR | |
| SCHEMBL4580654 | 0.92 | TK1 (0.50) | TK1TOP2ARNASE1DHFR | |
| SCHEMBL4580652 | 0.92 | TK1 (0.50) | TK1TOP2ARNASE1DHFR | |
| SCHEMBL22314627 | 0.90 | TK1 (0.51) | TK1TOP2ARNASE1DHFR | |
| SCHEMBL25372106 | 0.89 | LMNA (0.47) | TK1TOP2ARNASE1 | |
| SCHEMBL22020929 | 0.87 | TK1 (0.46) | TK1TOP2ARNASE1DHFR | |
| SCHEMBL22021510 | 0.87 | TK1 (0.46) | TK1TOP2ARNASE1DHFR | |
| SCHEMBL22020923 | 0.86 | TK1 (0.48) | TK1TOP2ARNASE1DHFR | |
| SCHEMBL25752294 | 0.86 | TK1 (0.45) | TK1TOP2ARNASE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021234459-A9 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2022-02-03 | — | — | WO | disclosed |
| WO-2021234459-A2 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |