Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ADH1C | P00326 | 2/20 | 0.40 |
| ▸ | ADH1A | P07327 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.37 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | ADH1B | P00325 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4265583 | 0.79 | JAK2 (0.36) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL25767748 | 0.79 | ALDH1A1 (0.43) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL25754601 | 0.78 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL3220299 | 0.76 | KMT2A (0.45) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL762461 | 0.75 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL2185721 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL3364682 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL2592782 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL24052200 | 0.73 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AKDM4EUSP2 | |
| SCHEMBL15867020 | 0.72 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EUSP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023220440-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2023-11-16 | — | — | WO | disclosed |
| WO-2021234459-A9 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2022-02-03 | — | — | WO | disclosed |
| WO-2021234459-A2 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |