Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | ADH1C | P00326 | 2/20 | 0.43 |
| ▸ | ADH1A | P07327 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 2/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | ADH1B | P00325 | 1/20 | 0.39 |
| ▸ | PKM | P14618 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5415709 | 0.87 | — | — | |
| SCHEMBL762461 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL2185721 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL24052200 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL2592782 | 0.76 | ALDH1A1 (0.48) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL15867020 | 0.75 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL4188937 | 0.75 | ADH1A (0.37) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL2585496 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL2592494 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EHPGD | |
| SCHEMBL12520057 | 0.74 | ALDH1A1 (0.47) | ALDH1A1MEN1KMT2AKDM4EHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12545669-B2 | Cycloalkyl and heterocycloalkyl benzisoxazole sulfonamide derivatives | PFIZER INC. (US) | 2026-02-10 | — | — | US | disclosed |
| WO-2025136811-A1 | CHEMICAL COMPOUNDS AND USES THEREOF | IDEAYA BIOSCIENCES, INC. (US) | 2025-06-26 | — | — | WO | disclosed |
| US-20250051343-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. | 2025-02-13 | — | — | US | disclosed |
| CN-119301096-A | Inhibitors of MYST family lysine acetyltransferase | 伊索斯泰里克斯公司 | 2025-01-10 | — | — | CN | disclosed |
| US-11976075-B2 | Inhibitors of the MYST family of lysine acetyl transferases | Isosterix, Inc. | 2024-05-07 | — | — | US | disclosed |
| US-11976075-B2 | Inhibitors of the MYST family of lysine acetyl transferases | Isosterix, Inc. | 2024-05-07 | — | — | US | disclosed |
| WO-2023192817-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. (US) | 2023-10-05 | — | — | WO | disclosed |
| US-20230303580-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. | 2023-09-28 | — | — | US | disclosed |
| US-20230303580-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | Isosterix, Inc. | 2023-09-28 | — | — | US | disclosed |
| US-20220251075-A1 | Cycloalkyl and Heterocycloalkyl Benzisoxazole Sulfonamide Derivatives | PFIZER INC. | 2022-08-11 | — | — | US | disclosed |
| EP-1303503-A2 | ANILINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| EP-1303486-A1 | PYRROLIDINE DERIVATIVES AS METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2003-04-23 | — | — | EP | disclosed |
| US-20020128247-A1 | Beta3 agonists and uses thereof | DOW ROBERT L (US) | 2002-09-12 | — | — | US | disclosed |
| EP-1236723-A1 | Sulfamide derivatives useful as beta3 agonists and pharmaceutical uses thereof | Pfizer Products Inc. (US) | 2002-09-04 | — | — | EP | disclosed |
| US-20020040146-A1 | Pyrrolidine derivatives | F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) | 2002-04-04 | — | — | US | disclosed |
| US-20020038025-A1 | Analine derivatives as OSC inhibitors | F.HOFFMANN-LA ROCHE AG (CH) | 2002-03-28 | — | — | US | disclosed |
| WO-2002008185-A1 | PYRROLIDINE DERIVATIVES AS METALLOPROTEASE INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-31 | — | — | WO | disclosed |
| WO-2002006189-A2 | ANILINE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-01-24 | — | — | WO | disclosed |
| EP-0804422-A1 | 4-ARYL- AND 4-HETEROARYL -5-OXOPYRAZOLINE DERIVATIVES HAVING PESTICIDAL PROPERTIES | Novartis AG (CH) | 1997-11-05 | — | — | EP | disclosed |
| WO-1996021652-A1 | 4-ARYL- AND 4-HETEROARYL -5-OXOPYRAZOLINE DERIVATIVES HAVING PESTICIDAL PROPERTIES | NOVARTIS AG (CH) | 1996-07-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20250051343-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | KAT6A, KAT6B, KAT2A | ALDH1A1 1618/4885MEN1 1988/4885KMT2A 22/4885 |
| US-20220251075-A1 | Cycloalkyl and Heterocycloalkyl Benzisoxazole Sulfonamide Derivatives | BRIX1, CCNA1, RB1 | ALDH1A1 1117/4885MEN1 1605/4885KMT2A 980/4885 |
| US-20230303580-A1 | INHIBITORS OF THE MYST FAMILY OF LYSINE ACETYL TRANSFERASES | KAT6A, KAT6B, KAT2A | ALDH1A1 1618/4885MEN1 1988/4885KMT2A 22/4885 |
| US-20020040146-A1 | Pyrrolidine derivatives | PREP, PEPD, MMP3 | ALDH1A1 1186/4885MEN1 3251/4885KMT2A 2324/4885 |
| US-20020038025-A1 | Analine derivatives as OSC inhibitors | LSS, CYP51A1, CYP46A1 | ALDH1A1 864/4885MEN1 615/4885KMT2A 3898/4885 |
| US-12545669-B2 | Cycloalkyl and heterocycloalkyl benzisoxazole sulfonamide derivatives | NHERF1, CBX8, BCL9 | ALDH1A1 1527/4885MEN1 1756/4885KMT2A 82/4885 |
| US-11976075-B2 | Inhibitors of the MYST family of lysine acetyl transferases | KAT6A, KAT6B, KAT2A | ALDH1A1 1618/4885MEN1 1988/4885KMT2A 22/4885 |
| US-20020128247-A1 | Beta3 agonists and uses thereof | ADRB3, ADRB1, ADRB2 | ALDH1A1 764/4885MEN1 3742/4885KMT2A 3877/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.