Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.50 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | HTT | P42858 | 3/20 | 0.38 |
| ▸ | F2 | P00734 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | KCNH3 | Q9ULD8 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prometryn SCHEMBL7657627 | 0.87 | MAPK1 (0.56) | MAPK1SMN1; SMN2TSHRHSD17B10GAA | |
| Prometryn SCHEMBL7622 | 0.87 | MAPK1 (0.56) | MAPK1SMN1; SMN2TSHRHSD17B10GAA | |
| Prometryn SCHEMBL20723889 | 0.85 | GAA (0.58) | MAPK1SMN1; SMN2TSHRHSD17B10GAA | |
| SCHEMBL9970686 | 0.80 | GAA (0.61) | MAPK1GAATDP1ALDH1A1LMNA | |
| SCHEMBL15599529 | 0.80 | GAA (0.54) | MAPK1GAATDP1ALDH1A1LMNA | |
| SCHEMBL29435432 | 0.80 | MAPK1 (0.50) | MAPK1SMN1; SMN2TSHRHSD17B10GAA | |
| SCHEMBL8827500 | 0.80 | MAPK1 (0.50) | MAPK1SMN1; SMN2TSHRHSD17B10GAA | |
| SCHEMBL66639 | 0.80 | MAPK1 (0.50) | MAPK1SMN1; SMN2TSHRHSD17B10GAA | |
| SCHEMBL2106591 | 0.78 | MAPK1 (0.53) | MAPK1HSP90AB1SMN1; SMN2TSHRHSD17B10 | |
| SCHEMBL11678083 | 0.78 | GAA (0.67) | MAPK1SMN1; SMN2TSHRHSD17B10GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021234459-A9 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2022-02-03 | — | — | WO | disclosed |
| WO-2021234459-A2 | DOUBLE STRANDED OLIGONUCLEOTIDE COMPOSITIONS AND METHODS RELATING THERETO | WAVE LIFE SCIENCES LTD. (SG) | 2021-11-25 | — | — | WO | disclosed |
| CN-1102858-A | New variety of drechslera monoceras, weed control compositions containing the same as an effective ingredient and weed control methods using the same | MITSUI TOATSU CHEMICALS (JP) | 1995-05-24 | — | — | CN | disclosed |