Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK1 | P28482 | 3/20 | 0.56 |
| ▸ | GAA | P10253 | 5/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | KCNH3 | Q9ULD8 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Prometryn SCHEMBL7622 | 1.00 | MAPK1 (0.56) | MAPK1GAATDP1HTTLMNA | |
| Prometryn SCHEMBL20723889 | 0.98 | GAA (0.58) | MAPK1GAATDP1HTTLMNA | |
| SCHEMBL29435432 | 0.92 | MAPK1 (0.50) | MAPK1GAATDP1HTTLMNA | |
| SCHEMBL66639 | 0.92 | MAPK1 (0.50) | MAPK1GAATDP1HTTLMNA | |
| SCHEMBL8827500 | 0.92 | MAPK1 (0.50) | MAPK1GAATDP1HTTLMNA | |
| Prometryn SCHEMBL5542826 | 0.88 | TSHR (0.48) | MAPK1GAATDP1HTTLMNA | |
| SCHEMBL24059309 | 0.87 | MAPK1 (0.50) | MAPK1GAATDP1HTTLMNA | |
| Prometryn SCHEMBL7945620 | 0.87 | POLB (0.54) | MAPK1GAAHTTLMNATSHR | |
| Ametryne SCHEMBL8541067 | 0.87 | POLB (0.54) | MAPK1GAAHTTLMNATSHR | |
| Ametryne SCHEMBL65196 | 0.87 | POLB (0.54) | MAPK1GAAHTTLMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 69 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0009620-B1 | HERBICIDES AND THEIR APPLICATION TO THE CONTROL OF WEEDS | HOECHST AKTIENGESELLSCHAFT (DE) | 1981-08-05 | — | — | EP | claimed |
| EP-0009620-A1 | Herbicides and their application to the control of weeds | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-16 | — | — | EP | claimed |
| EP-1223988-A1 | ANTISENSE MODULATION OF TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME (TACE) EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001030360-A1 | MODULATION OF L-SELECTIN SHEDDING VIA INHIBITION OF TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME (TACE) | ISIS PHARMACEUTICALS, INC. (US) | 2001-05-03 | — | — | WO | disclosed |
| WO-2001030395-A1 | ANTISENSE MODULATION OF TUMOR NECROSIS FACTOR ALPHA CONVERTING ENZYME (TACE) EXPRESSION | ISIS PHARMACEUTICALS, INC. (US) | 2001-05-03 | — | — | WO | disclosed |
| EP-0902681-A1 | INHIBITION OF SELECTIN BINDING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1999-03-24 | — | — | EP | disclosed |
| EP-0574418-B1 | ARYL SULPHONYL UREA COMPOUNDS, A METHOD OF PREPARING THEM, AND THEIR USE AS HERBICIDES AND GROWTH REGULATORS | HOECHST SCHERING AGREVO GMBH (DE) | 1998-11-11 | — | — | EP | disclosed |
| US-5688745-A | Arylsulfonylureas and their use as herbicides and growth regulators | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-11-18 | — | — | US | disclosed |
| WO-1997031625-A1 | INHIBITION OF SELECTIN BINDING | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 1997-09-04 | — | — | WO | disclosed |
| US-5463081-A | Chemical intermediates | HOECHST AKTIENGESELLSCHAFT (DE) | 1995-10-31 | — | — | US | disclosed |
| WO-1992020684-A1 | HERBICIDAL OXATRICYCLIC ETHERS | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1992-11-26 | — | — | WO | disclosed |
| US-4278613-A | ANTIDOTES | CIBA-GEIGY CORPORATION (US) | 1981-07-14 | — | — | US | disclosed |
| US-4269775-A | DERIVATIVES OF PHENYL OR NAPHTHYL ACETONITRILE OXIME-ALKYLENE-DIETHERS; ANTIDOTES FOR HERBICIDES | CIBA-GEIGY CORPORATION (US) | 1981-05-26 | — | — | US | disclosed |
| EP-0019796-A1 | Propionic acid esters, preparation of these compounds, herbicides containing these compounds as active substances, and the use of such compounds and agents for combating weeds | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft (CH) | 1980-12-10 | — | — | EP | disclosed |
| EP-0012158-A2 | Oxime derivatives and their use in the protection of cultivated plants | CIBA-GEIGY AG (CH) | 1980-06-25 | — | — | EP | disclosed |
| EP-0010588-A2 | Sulfur-containing oxime compounds and their use to protect cultivated plants | CIBA-GEIGY AG (CH) | 1980-05-14 | — | — | EP | disclosed |
| EP-0011047-A2 | Oxime derivatives to protect cultivated plants | CIBA-GEIGY AG (CH) | 1980-05-14 | — | — | EP | disclosed |
| EP-0010143-A2 | Oxime derivatives to protect cultivated plants | CIBA-GEIGY AG (CH) | 1980-04-30 | — | — | EP | disclosed |
| EP-0010058-A1 | Process and compositions for the protection of plant cultures against the phytotoxic action of strong herbicides; oxime ether derivatives | CIBA-GEIGY AG (CH) | 1980-04-16 | — | — | EP | disclosed |
| EP-0009620-A1 | Herbicides and their application to the control of weeds | HOECHST AKTIENGESELLSCHAFT (DE) | 1980-04-16 | — | — | EP | disclosed |