Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 4/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.50 |
| ▸ | KCNH3 | Q9ULD8 | 3/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15599529 | 0.94 | GAA (0.54) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL15131652 | 0.91 | GAA (0.52) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL8041736 | 0.88 | GAA (0.74) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL13208246 | 0.85 | GAA (0.58) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL11451349 | 0.84 | GAA (0.45) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL20814490 | 0.84 | GAA (0.75) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL24059309 | 0.80 | MAPK1 (0.50) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL20117984 | 0.78 | GAA (0.61) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL29368367 | 0.78 | GAA (0.61) | GAATDP1HTTMAPK1LMNA | |
| SCHEMBL14869317 | 0.76 | KCNH3 (0.75) | GAATDP1KMT2AMEN1KCNH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012083190-A1 | INSECT ODORANT RECEPTOR ANTAGONISTS | THE ROCKEFELLER UNIVERSITY (US) | 2012-06-21 | — | — | WO | disclosed |