SCHEMBL240599

SCHEMBL240599

N#Cc1cc(N)c(N)cc1C#N

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.48
GAA P10253 2/20 0.48
LMNA P02545 2/20 0.48
MAPT P10636 2/20 0.48
HPGD P15428 2/20 0.48
MEN1 O00255 1/20 0.48
HTT P42858 1/20 0.48
KMT2A Q03164 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.48
PTK2 Q05397 1/20 0.44
ALDH1A1 P00352 3/20 0.43
USP2 O75604 1/20 0.43
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
KHK P50053 1/20 0.37
CSNK1A1 P48729 1/20 0.34
CLK4 Q9HAZ1 1/20 0.34
USP8 P40818 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29420723 1.00 KDM4E (0.48) KDM4EGAALMNAMAPTHPGD
SCHEMBL21897806 0.88 KDM4E (0.50) KDM4EGAALMNAMAPTHPGD
SCHEMBL6630371 0.87 KDM4E (0.43) KDM4EGAALMNAMAPTHPGD
SCHEMBL29420709 0.85 KDM4E (0.42) KDM4EGAALMNAMAPTHPGD
SCHEMBL10694574 0.85 KDM4E (0.42) KDM4EGAALMNAMAPTHPGD
Hydrochloric Acid SCHEMBL28454054 0.84 KDM4E (0.42) KDM4EGAALMNAMAPTHPGD
SCHEMBL28525051 0.83 KDM4E (0.41) KDM4EGAALMNAMAPTHPGD
SCHEMBL29553645 0.83 KDM4E (0.41) KDM4EGAALMNAMAPTHPGD
SCHEMBL22977532 0.81 KDM4E (0.41) KDM4EGAALMNAMAPTHPGD
SCHEMBL1796492 0.81 CD44 (0.42) KDM4EGAALMNAMAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 137 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119751421-A Near infrared luminescent material and preparation method and application thereof 宝鸡文理学院 2025-04-04 CN claimed
CN-119613841-A Flame-retardant high-toughness HDPE (high-density polyethylene) resin and preparation method thereof 江苏欣宝科技股份有限公司 2025-03-14 CN claimed
CN-119462532-A Near infrared material suitable for solution processing and preparation method and application thereof 广东工业大学 2025-02-18 CN claimed
CN-115925641-B Preparation of D-A structure organic micromolecular photo-thermal material and application of D-A structure organic micromolecular photo-thermal material in cogeneration of water and electricity 东北林业大学 2024-08-23 CN claimed
CN-118324701-A Photosensitive nano prodrug for photodynamic-immune cooperative treatment of tumor as well as preparation method and application thereof 西安交通大学 2024-07-12 CN claimed
CN-118271295-A Dibenzophenazine derivative luminescent material and preparation method and application thereof 大连理工大学 2024-07-02 CN claimed
CN-117343020-A Orange-red photo-thermal activation delay fluorescent material and preparation method and application thereof 广东工业大学 2024-01-05 CN claimed
CN-115925641-A Preparation of D-A structure organic micromolecule photo-thermal material and application of material in water and electricity co-production 东北林业大学 2023-04-07 CN claimed
CN-115819421-A Deep red light/near infrared organic electroluminescent material, preparation method thereof and application thereof in preparing OLED 华南理工大学 2023-03-21 CN claimed
CN-113816911-B Red light material with multiple light emitting units and preparation method and application thereof 季华实验室 2022-03-08 CN claimed
CN-113816911-A Red light material with multiple light emitting units and preparation method and application thereof 季华实验室 2021-12-21 CN claimed
CN-111808097-B Solvent yellow 184 derivative and preparation method and application thereof 厦门大学 2021-10-22 CN claimed
CN-112409364-A Hexaazanaphthalene derivative and preparation method and application thereof 常州大学 2021-02-26 CN claimed
CN-111808097-A Solvent yellow 184 derivative and preparation method and application thereof 厦门大学 2020-10-23 CN claimed
CN-109030577-B Room temperature NH3Sensor and preparation method thereof 吉林大学 2020-05-05 CN claimed
US-12617793-B2 Organic electron transfer mediator and device comprising same I-SENS, INC. (KR) 2026-05-05 US disclosed
EP-4723845-A1 COMPOUND, ORGANIC THIN FILM, PHOTOELECTRIC CONVERSION ELEMENT, IMAGING ELEMENT, PHOTOSENSOR, AND SOLID-STATE IMAGING DEVICE MITSUBISHI GAS CHEMICAL COMPANY, INC. (JP) 2026-04-08 EP disclosed
CN-101003516-A Dentritic pattern compound, preparation method and application CHINESE ACAD INST CHEMISTRY (CN) 2007-07-25 CN disclosed
WO-2005123737-A9 CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF TY OF ARIZONA ARIZONA BOARD OF (US) 2006-04-06 WO disclosed
WO-2005123737-A2 CHARGE-TRANSPORT MATERIALS, METHODS OF FABRICATION THEREOF, AND METHODS OF USE THEREOF ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) 2005-12-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12617793-B2 Organic electron transfer mediator and device comprising same SCO2, ETFB, MT-CO1 KDM4E 2052/4885GAA 4837/4885LMNA 2600/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.