Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 18/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTR6 | P50406 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22278486 | 0.91 | RORC (0.43) | RORC | |
| SCHEMBL22278745 | 0.90 | RORC (0.43) | RORCCYP2C9HPGDCYP2C19HTR6 | |
| SCHEMBL22278690 | 0.89 | RORC (0.47) | RORCPOLBCYP2C9HPGDCYP2C19 | |
| SCHEMBL22278483 | 0.88 | RORC (0.43) | RORCPOLBCYP2C9HPGDCYP2C19 | |
| SCHEMBL22278706 | 0.88 | RORC (0.41) | RORCHPGDHTR6 | |
| SCHEMBL22278490 | 0.87 | RORC (0.47) | RORCPOLBCYP2C9HPGDCYP2C19 | |
| SCHEMBL22278511 | 0.86 | HPGD (0.49) | RORCPOLBCYP2C9HPGDCYP2C19 | |
| SCHEMBL22278760 | 0.86 | RORC (0.42) | RORC | |
| SCHEMBL22278716 | 0.85 | RORC (0.46) | RORCPOLBCYP2C9HPGDCYP2C19 | |
| SCHEMBL22278765 | 0.82 | RORC (0.45) | RORCPOLBCYP2C9HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3915977-A1 | 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2021-12-01 | — | — | EP | disclosed |