Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 19/20 | 0.43 |
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24061238 | 0.89 | KDM2B (0.41) | RORCHTR6 | |
| SCHEMBL22278568 | 0.85 | RORC (0.44) | RORCHTR6 | |
| SCHEMBL22278739 | 0.84 | HTR6 (0.42) | RORCHTR6 | |
| SCHEMBL24061202 | 0.82 | RORC (0.54) | RORC | |
| SCHEMBL22278383 | 0.82 | RORC (0.46) | RORCHTR6 | |
| SCHEMBL22278556 | 0.82 | RORC (0.46) | RORCHTR6 | |
| SCHEMBL22278486 | 0.81 | RORC (0.43) | RORC | |
| SCHEMBL22278612 | 0.81 | RORC (0.44) | RORCHTR6 | |
| SCHEMBL22278490 | 0.80 | RORC (0.47) | RORCHTR6 | |
| SCHEMBL22278544 | 0.80 | RORC (0.44) | RORC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3915977-A1 | 1,2,3,4-TETRAHYDROQUINOXALINE DERIVATIVE, PREPARATION METHOD THEREFOR AND APPLICATION THEREOF | Abbisko Therapeutics Co., Ltd. (CN) | 2021-12-01 | — | — | EP | disclosed |