SCHEMBL24062787

SCHEMBL24062787

CCN(CC)CCNC(=O)C1C2C=CC(C2)C1C(C)=O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ SIGMAR1 Q99720 1/20 0.47
▸ FPR3 P25089 3/20 0.44
▸ FPR2 P25090 3/20 0.44
▸ ALDH1A1 P00352 3/20 0.43
▸ TAAR1 Q96RJ0 3/20 0.43
▸ NPSR1 Q6W5P4 1/20 0.43
▸ POLB P06746 4/20 0.40
▸ KMT2A Q03164 1/20 0.40
▸ HTT P42858 1/20 0.40
▸ TDP1 Q9NUW8 1/20 0.40
▸ TSHR P16473 2/20 0.40
▸ NFKB1 P19838 1/20 0.38
▸ KCNH2 Q12809 1/20 0.38
▸ STAT3 P40763 1/20 0.38
▸ SLC22A2 O15244 1/20 0.38
▸ SLC22A1 O15245 1/20 0.38
▸ LMNA P02545 1/20 0.38
▸ ACHE P22303 1/20 0.38
▸ MAPK1 P28482 1/20 0.38
▸ CYP2C19 P33261 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23489118 1.00 SIGMAR1 (0.47) SIGMAR1FPR3FPR2ALDH1A1TAAR1
SCHEMBL24503495 0.87 SIGMAR1 (0.46) SIGMAR1FPR3FPR2ALDH1A1TAAR1
SCHEMBL21716641 0.85 ALDH1A1 (0.46) FPR3FPR2ALDH1A1TAAR1NPSR1
SCHEMBL21716640 0.85 ALDH1A1 (0.46) FPR3FPR2ALDH1A1TAAR1NPSR1
SCHEMBL24506182 0.85 ALDH1A1 (0.46) FPR3FPR2ALDH1A1TAAR1NPSR1
SCHEMBL21884004 0.85 SIGMAR1 (0.44) SIGMAR1FPR3FPR2ALDH1A1TAAR1
SCHEMBL24062717 0.85 ALDH1A1 (0.47) SIGMAR1FPR3FPR2ALDH1A1TAAR1
SCHEMBL24334709 0.73 SIGMAR1 (0.46) SIGMAR1FPR3FPR2ALDH1A1TAAR1
SCHEMBL24503494 0.72 ALDH1A1 (0.44) FPR3FPR2ALDH1A1TAAR1NPSR1
SCHEMBL24334710 0.72 NPC1 (0.46) SIGMAR1FPR3FPR2ALDH1A1TAAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4011396-A1 RELEASABLE CONJUGATES QuiaPEG Pharmaceuticals AB (SE) 2022-06-15 — — EP disclosed
US-20220118055-A1 RELEASABLE GLP-1 CONJUGATES FISH & RICHARDSON PC 2022-04-21 — — US disclosed
EP-3592393-B1 RELEASABLE CONJUGATES QUIAPEG PHARMACEUTICALS AB (SE) 2021-12-01 — — EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220118055-A1 RELEASABLE GLP-1 CONJUGATES GLP1R, GIPR, IAPP SIGMAR1 2651/4885FPR3 849/4885FPR2 1559/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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