Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | NNMT | P40261 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 4/20 | 0.31 |
| ▸ | ACE | P12821 | 3/20 | 0.31 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28518825 | 0.81 | CYP46A1 (0.38) | NNMTALDH1A1HSD17B10 | |
| SCHEMBL2608533 | 0.74 | GAA (0.41) | MAPTGAANNMT | |
| SCHEMBL16464959 | 0.73 | MAPT (0.56) | MAPTGAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL16464958 | 0.73 | MAPT (0.56) | MAPTGAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL2608547 | 0.73 | MAPT (0.56) | MAPTGAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL29550106 | 0.73 | MAPT (0.56) | MAPTGAAALDH1A1KDM4EHSD17B10 | |
| Hydrochloric Acid SCHEMBL18103843 | 0.72 | MAPT (0.54) | MAPTGAAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL28595338 | 0.71 | NNMT (0.32) | NNMT | |
| SCHEMBL29153653 | 0.71 | NNMT (0.39) | MAPTGAANNMTALDH1A1KDM4E | |
| SCHEMBL29153655 | 0.71 | NNMT (0.39) | MAPTGAANNMTALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3916003-A1 | N-METHYL-D-ASPARTATE RECEPTOR MODULATORS AND METHODS OF MAKING AND USING SAME | Naurex, Inc. (US) | 2021-12-01 | — | — | EP | disclosed |