Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | AGBL2 | Q5U5Z8 | 1/20 | 0.38 |
| ▸ | GLA | P06280 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.34 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.34 |
| ▸ | ITGA2 | P17301 | 1/20 | 0.34 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29153655 | 1.00 | NNMT (0.39) | NNMTGAAMAPTAGBL2GLA | |
| SCHEMBL29153652 | 0.85 | SMN1; SMN2 (0.43) | NNMTGAAAGBL2SMN1; SMN2KDM4E | |
| SCHEMBL29153654 | 0.85 | SMN1; SMN2 (0.43) | NNMTGAAAGBL2SMN1; SMN2KDM4E | |
| SCHEMBL30104825 | 0.85 | SMN1; SMN2 (0.43) | NNMTGAAAGBL2SMN1; SMN2KDM4E | |
| SCHEMBL2608533 | 0.78 | GAA (0.41) | NNMTGAAMAPTITGB1ITGA2 | |
| SCHEMBL29153690 | 0.77 | ALDH1A1 (0.35) | NNMTGAAAGBL2ALDH1A1SSTR4 | |
| SCHEMBL29153693 | 0.77 | ALDH1A1 (0.35) | NNMTGAAAGBL2ALDH1A1SSTR4 | |
| SCHEMBL30104866 | 0.77 | ALDH1A1 (0.35) | NNMTGAAAGBL2ALDH1A1SSTR4 | |
| SCHEMBL27813563 | 0.74 | GAA (0.55) | GAAMAPTHPGDKDM4EALDH1A1 | |
| SCHEMBL29302233 | 0.71 | GAA (0.45) | GAAMAPTITGB1ITGA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117396485-A | PARP7 inhibitors | 轩竹生物科技股份有限公司 | 2024-01-12 | — | — | CN | disclosed |