SCHEMBL24064883

SCHEMBL24064883

NCCCN(N)CCNCCNN

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CASP2 P42575 2/20 0.42
CA12 O43570 5/20 0.40
CA6 P23280 5/20 0.40
CA7 P43166 5/20 0.40
CA9 Q16790 5/20 0.40
CA14 Q9ULX7 5/20 0.40
CA5B Q9Y2D0 5/20 0.40
CA2 P00918 4/20 0.40
CA4 P22748 4/20 0.40
CA5A P35218 4/20 0.40
ALOX15 P16050 4/20 0.40
TDP1 Q9NUW8 3/20 0.40
LMNA P02545 3/20 0.40
CA3 P07451 3/20 0.40
CYP2C19 P33261 2/20 0.40
CYP2C9 P11712 2/20 0.40
CA1 P00915 2/20 0.40
ALDH1A1 P00352 1/20 0.40
TP53 P04637 1/20 0.40
KDM4E B2RXH2 2/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL991275 0.85 CA12 (0.55) CASP2CA12CA6CA7CA9
SCHEMBL10718770 0.78 CA12 (0.55) CASP2CA12CA6CA7CA9
SCHEMBL28163640 0.75 CYP2C19 (0.54) CASP2CA12CA6CA7CA9
SCHEMBL902205 0.74
SCHEMBL670241 0.74 CA12 (0.73) CASP2CA12CA6CA7CA9
SCHEMBL11199787 0.74 CA12 (0.73) CASP2CA12CA6CA7CA9
SCHEMBL5031643 0.74 NFKB1 (0.43) CASP2CA12CA6CA7CA9
SCHEMBL3628938 0.72 CYP2C19 (0.46) CASP2CA12CA6CA7CA9
SCHEMBL4848867 0.70 CA12 (0.65) CASP2CA12CA6CA7CA9
SCHEMBL27477119 0.70 CYP2C19 (0.48) CASP2CA12CA6CA7CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021243278-A1 WETTING AGENT FOR INVERT EMULSION DRILLING FLUIDS SAUDI ARABIAN OIL COMPANY (SA) 2021-12-02 WO disclosed