Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.56 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.54 |
| ▸ | CTSS | P25774 | 10/20 | 0.47 |
| ▸ | CTSK | P43235 | 9/20 | 0.47 |
| ▸ | CTSB | P07858 | 4/20 | 0.47 |
| ▸ | ACE | P12821 | 1/20 | 0.46 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.46 |
| ▸ | CTSL | P07711 | 2/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
| ▸ | ERAP2 | Q6P179 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28353206 | 0.94 | CTSS (0.48) | LNPEPKLK5CTSSCTSKCTSB | |
| SCHEMBL29529273 | 0.94 | CTSS (0.48) | LNPEPKLK5CTSSCTSKCTSB | |
| SCHEMBL20529400 | 0.90 | KLK5 (0.52) | LNPEPKLK5CTSSCTSKCTSB | |
| SCHEMBL7102789 | 0.90 | KLK5 (0.52) | LNPEPKLK5CTSSCTSKCTSB | |
| SCHEMBL7103652 | 0.89 | KLK5 (0.51) | LNPEPKLK5CTSSCTSKCTSB | |
| SCHEMBL26699639 | 0.89 | KLK5 (0.51) | LNPEPKLK5CTSSCTSKCTSB | |
| SCHEMBL26699643 | 0.89 | KLK5 (0.51) | LNPEPKLK5CTSSCTSKCTSB | |
| SCHEMBL21639310 | 0.89 | ACE (0.59) | CTSSCTSKCTSBACECTSL | |
| SCHEMBL21639309 | 0.89 | ACE (0.59) | CTSSCTSKCTSBACECTSL | |
| SCHEMBL21664168 | 0.88 | AAK1 (0.47) | LNPEPKLK5CTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210369855-A1 | CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE | HANGZHOU DAC BIOTECH CO., LTD. (CN) | 2021-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369855-A1 | CONJUGATION OF A CYTOTOXIC DRUG WITH BIS-LINKAGE | CD4, MCL1, CCNB1 | LNPEP 631/4885KLK5 4107/4885CTSS 1455/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.