Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.47 |
| ▸ | LNPEP | Q9UIQ6 | 1/20 | 0.47 |
| ▸ | CTSS | P25774 | 10/20 | 0.45 |
| ▸ | CTSK | P43235 | 9/20 | 0.45 |
| ▸ | CTSB | P07858 | 4/20 | 0.45 |
| ▸ | ACE | P12821 | 1/20 | 0.44 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.42 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.42 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
| ▸ | PPARA | Q07869 | 1/20 | 0.42 |
| ▸ | TACR1 | P25103 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26699639 | 1.00 | KLK5 (0.51) | KLK5CTSLLNPEPCTSSCTSK | |
| SCHEMBL30898974 | 0.89 | ACE (0.56) | CTSLCTSSCTSKCTSBACE | |
| SCHEMBL5893125 | 0.89 | ACE (0.56) | CTSLCTSSCTSKCTSBACE | |
| SCHEMBL24065192 | 0.89 | LNPEP (0.56) | KLK5CTSLLNPEPCTSSCTSK | |
| SCHEMBL5782787 | 0.87 | CA2 (0.52) | KLK5CTSLCTSSCTSKCTSB | |
| SCHEMBL7039592 | 0.87 | CA2 (0.52) | KLK5CTSLCTSSCTSKCTSB | |
| SCHEMBL16095397 | 0.86 | KLK5 (0.51) | KLK5CTSLCTSSCTSKCTSB | |
| SCHEMBL18843321 | 0.86 | KLK5 (0.51) | KLK5CTSLCTSSCTSKCTSB | |
| SCHEMBL7103652 | 0.86 | KLK5 (0.51) | KLK5CTSLLNPEPCTSSCTSK | |
| SCHEMBL24534557 | 0.86 | KLK5 (0.51) | KLK5CTSLCTSSCTSKCTSB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2023226950-A1 | PEPTIDOMIMETIC STAT PROTEIN DEGRADER, COMPOSITION AND USE THEREOF | 杭州和正医药有限公司 | 2023-11-30 | — | — | WO | disclosed |
| CN-117126231-A | Peptoid STAT protein degradation agent, composition and application thereof | 杭州和正医药有限公司 | 2023-11-28 | — | — | CN | disclosed |