SCHEMBL24065737

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30250301	0.90	CFTR (0.49)	FLT1KDRARCYP3A4SMN1; SMN2
	SCHEMBL2239932	0.89	PDGFRB (0.45)	PDGFRBFGFR1PDGFRAFLT1FGFR3
	SCHEMBL16647610	0.85	ALDH1A1 (0.51)	ARSMN1; SMN2ALDH1A1LMNAMAPT
	SCHEMBL2390749	0.84	CFTR (0.62)	PDGFRBFGFR1PDGFRAFLT1FGFR3
	SCHEMBL1301766	0.84	CHEK1 (0.46)	PDGFRBFGFR1PDGFRAFLT1FGFR3
	SCHEMBL2247382	0.83	PDGFRB (0.50)	PDGFRBFGFR1PDGFRAFLT1FGFR3
	SCHEMBL2895340	0.83	PDGFRB (0.50)	PDGFRBFGFR1PDGFRAFLT1FGFR3
	SCHEMBL2035638	0.83	CFTR (0.43)	PDGFRBFGFR1PDGFRAFLT1FGFR3
	SCHEMBL2597417	0.83	CFTR (0.43)	PDGFRBFGFR1PDGFRAFLT1FGFR3
	SCHEMBL22833807	0.83	CFTR (0.43)	PDGFRBFGFR1PDGFRAFLT1FGFR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.