SCHEMBL24065786

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29944192	1.00	NOTUM (0.56)	NOTUMSOS1CFTRPTPN2MAPT
	SCHEMBL18382142	0.89	SOS1 (0.50)	NOTUMSOS1CFTRPTPN2NPSR1
	SCHEMBL28921143	0.88	SOS1 (0.49)	NOTUMSOS1CFTRPTPN2NPSR1
	SCHEMBL20471822	0.84	NOTUM (0.56)	NOTUMSOS1CFTRPTPN2MAPT
	SCHEMBL29835141	0.84	NOTUM (0.60)	NOTUMSOS1CFTRPTPN2MAPT
	SCHEMBL20150029	0.84	NOTUM (0.60)	NOTUMSOS1CFTRPTPN2MAPT
	SCHEMBL16647670	0.83	PTPN2 (0.43)	NOTUMSOS1PTPN2NPSR1KDM4E
	SCHEMBL23526150	0.83	NOTUM (0.55)	NOTUMSOS1CFTRPTPN2MAPT
	SCHEMBL3533161	0.83	CFTR (0.68)	NOTUMSOS1CFTRMAPTKDM4E
	SCHEMBL23525884	0.83	SOS1 (0.57)	NOTUMSOS1CFTRPTPN2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.