SCHEMBL24067909

SCHEMBL24067909

Nc1cccc(-c2ccc(-c3nc(-c4ccccc4)nc(-c4ccc(-c5cc(-c6ccccc6)c6c(c5-c5ccccc5)-c5cccc7cccc-6c57)cc4)n3)cc2)c1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 4/20 0.53
KMT2A Q03164 4/20 0.53
ALDH1A1 P00352 3/20 0.53
MAPT P10636 3/20 0.53
HPGD P15428 3/20 0.53
KDM4E B2RXH2 2/20 0.53
LMNA P02545 2/20 0.53
GLA P06280 1/20 0.53
MAOA P21397 1/20 0.45
NTRK1 P04629 1/20 0.38
NPC1 O15118 1/20 0.38
RAB9A P51151 1/20 0.38
CYP17A1 P05093 2/20 0.38
CYP3A4 P08684 2/20 0.38
CYP19A1 P11511 2/20 0.38
CYP11B1 P15538 2/20 0.38
CYP11B2 P19099 2/20 0.38
ATAD2 Q6PL18 1/20 0.37
PRKCZ Q05513 1/20 0.37
ADORA3 P0DMS8 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL24067908 0.93 MAPT (0.47) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL24067849 0.91 MAPT (0.63) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL16658500 0.89 ALDH1A1 (0.42) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL24067720 0.88 MAOA (0.47) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL24067731 0.88 HSD17B10 (0.46) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL24067843 0.88 MEN1 (0.60) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL24067728 0.87 HSD17B10 (0.42) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL24067872 0.87 HSD17B10 (0.42) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL17014576 0.84 MEN1 (0.48) MEN1KMT2AALDH1A1MAPTHPGD
SCHEMBL16658485 0.84 ALDH1A1 (0.37) MEN1KMT2AALDH1A1MAPTHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021241900-A1 COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME 주식회사 엘지화학 2021-12-02 WO disclosed