Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 1/20 | 0.48 |
| ▸ | MAP1LC3B | Q9GZQ8 | 9/20 | 0.47 |
| ▸ | CRBN | Q96SW2 | 6/20 | 0.47 |
| ▸ | BRD4 | O60885 | 4/20 | 0.47 |
| ▸ | IKZF3 | Q9UKT9 | 1/20 | 0.45 |
| ▸ | RIPK2 | O43353 | 1/20 | 0.44 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23765742 | 0.90 | CRBN (0.51) | STAT3MAP1LC3BCRBNBRD4IKZF3 | |
| SCHEMBL23772670 | 0.89 | MAP1LC3B (0.51) | STAT3MAP1LC3BCRBNBRD4IKZF3 | |
| SCHEMBL23772439 | 0.89 | MAP1LC3B (0.51) | STAT3MAP1LC3BCRBNBRD4IKZF3 | |
| SCHEMBL23772825 | 0.89 | MAP1LC3B (0.51) | STAT3MAP1LC3BCRBNBRD4IKZF3 | |
| SCHEMBL23766126 | 0.89 | MAP1LC3B (0.49) | STAT3MAP1LC3BCRBNBRD4IKZF3 | |
| SCHEMBL23037219 | 0.88 | CRBN (0.52) | MAP1LC3BCRBNBRD4IKZF3 | |
| SCHEMBL25756460 | 0.85 | MAP1LC3B (0.52) | STAT3MAP1LC3BCRBNBRD4IKZF3 | |
| SCHEMBL25031848 | 0.85 | MAP1LC3B (0.52) | STAT3MAP1LC3BCRBNBRD4IKZF3 | |
| SCHEMBL25032246 | 0.84 | MAP1LC3B (0.48) | STAT3MAP1LC3BCRBNBRD4IKZF3 | |
| SCHEMBL25756263 | 0.84 | MAP1LC3B (0.48) | STAT3MAP1LC3BCRBNBRD4IKZF3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210369853-A1 | TARGETED PROTEASE DEGRADATION PLATFORM | EUBULUS BIOTHERAPEUTICS INC. (CN) | 2021-12-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210369853-A1 | TARGETED PROTEASE DEGRADATION PLATFORM | PSMB1, MDM2, XIAP | STAT3 4225/4885MAP1LC3B 730/4885CRBN 284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.