Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 2/20 | 0.61 |
| ▸ | RAB9A | P51151 | 6/20 | 0.56 |
| ▸ | POLB | P06746 | 6/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 4/20 | 0.54 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.49 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA4 | P22748 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3892022 | 0.81 | HSD17B10 (0.53) | RAB9APOLBHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL19403373 | 0.81 | MAPT (0.47) | RAB9APOLBHSD17B10NPC1SMN1; SMN2 | |
| SCHEMBL19403427 | 0.80 | POLB (0.48) | CYP1A2RAB9APOLBHSD17B10SMN1; SMN2 | |
| SCHEMBL29812367 | 0.80 | POLB (0.48) | CYP1A2RAB9APOLBHSD17B10SMN1; SMN2 | |
| SCHEMBL7867128 | 0.79 | FFAR1 (0.55) | RAB9AHSD17B10NPC1SMN1; SMN2ALDH1A1 | |
| SCHEMBL19403380 | 0.79 | MTNR1A (0.50) | POLBHSD17B10SMN1; SMN2GAAALDH1A1 | |
| SCHEMBL4633858 | 0.79 | CYP1A2 (0.61) | CYP1A2RAB9APOLBHSD17B10NPC1 | |
| SCHEMBL19403441 | 0.78 | HSD17B10 (0.42) | CYP1A2POLBHSD17B10SMN1; SMN2ALDH1A1 | |
| SCHEMBL2561504 | 0.77 | CYP1A2 (0.73) | CYP1A2RAB9APOLBHSD17B10NPC1 | |
| SCHEMBL340809 | 0.77 | CYP1A2 (1.00) | CYP1A2RAB9APOLBNPC1HSP90AA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011104307-A2 | LIGANDS FOR ANTIBODY PURIFICATION BY AFFINITY CHROMATOGRAPHY | GRAFFINITY PHARMACEUTICALS GMBH (DE) | 2011-09-01 | — | — | WO | disclosed |