SCHEMBL19403373

SCHEMBL19403373

Cc1ccccc1SCC(=O)OC(C)(C)C

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.47
ALDH1A1 P00352 4/20 0.47
L3MBTL1 Q9Y468 3/20 0.47
ATM Q13315 1/20 0.45
HSD17B10 Q99714 2/20 0.45
POLB P06746 2/20 0.45
MEN1 O00255 3/20 0.44
KMT2A Q03164 3/20 0.44
NOTUM Q6P988 1/20 0.44
SMN1; SMN2 Q16637 3/20 0.42
LMNA P02545 2/20 0.42
RAB9A P51151 2/20 0.42
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
KDM4E B2RXH2 3/20 0.40
CCNB2 O95067 1/20 0.40
CCNE2 O96020 1/20 0.40
CDK1 P06493 1/20 0.40
CDK4 P11802 1/20 0.40
CCNB1 P14635 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3892022 0.84 HSD17B10 (0.53) MAPTALDH1A1HSD17B10POLBMEN1
SCHEMBL29812367 0.83 POLB (0.48) ALDH1A1L3MBTL1HSD17B10POLBMEN1
SCHEMBL19403427 0.83 POLB (0.48) ALDH1A1L3MBTL1HSD17B10POLBMEN1
SCHEMBL24022095 0.82 SMN1; SMN2 (0.44) MAPTALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL19403380 0.81 MTNR1A (0.50) MAPTALDH1A1ATMHSD17B10POLB
SCHEMBL2407025 0.81 CYP1A2 (0.61) MAPTALDH1A1HSD17B10POLBMEN1
SCHEMBL1549677 0.80 ALDH1A1 (0.42) MAPTALDH1A1L3MBTL1POLBSMN1; SMN2
SCHEMBL19403441 0.80 HSD17B10 (0.42) MAPTALDH1A1HSD17B10POLBMEN1
SCHEMBL7153877 0.80 L3MBTL1 (0.60) MAPTALDH1A1L3MBTL1ATMHSD17B10
SCHEMBL5416197 0.79 ALDH1A1 (0.44) MAPTALDH1A1L3MBTL1POLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10710061-B2 Ion pair catalysis of tungstate and molybdate NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2020-07-14 US disclosed
US-10710061-B2 Ion pair catalysis of tungstate and molybdate NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2020-07-14 US disclosed
US-20190105646-A1 ION PAIR CATALYSIS OF TUNGSTATE AND MOLYBDATE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2019-04-11 US disclosed
WO-2017164813-A1 ION PAIR CATALYSIS OF TUNGSTATE AND MOLYBDATE NANYANG TECHNOLOGICAL UNIVERSITY (SG) 2017-09-28 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10710061-B2 Ion pair catalysis of tungstate and molybdate PRDX3, PRDX4, PRDX2 MAPT 4402/4885ALDH1A1 1230/4885L3MBTL1 2115/4885
US-20190105646-A1 ION PAIR CATALYSIS OF TUNGSTATE AND MOLYBDATE PRDX3, PRDX4, PRDX6 MAPT 4507/4885ALDH1A1 1492/4885L3MBTL1 1863/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.