Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Alcohol SCHEMBL28979889 | 0.85 | — | — | |
| Ethylene Glycol SCHEMBL28840991 | 0.83 | — | — | |
| Isopropyl Alcohol SCHEMBL156522 | 0.82 | — | — | |
| Isopropyl Alcohol SCHEMBL9460837 | 0.82 | TSHR (0.60) | — | |
| Alcohol SCHEMBL2059115 | 0.82 | — | — | |
| Isopropyl Alcohol SCHEMBL28198950 | 0.82 | TSHR (0.60) | — | |
| Isopropyl Alcohol SCHEMBL5167390 | 0.82 | TSHR (0.60) | — | |
| Isopropyl Alcohol SCHEMBL3277962 | 0.82 | TSHR (0.60) | — | |
| Isopropyl Alcohol SCHEMBL16457736 | 0.82 | TSHR (0.60) | — | |
| Butyl Alcohol SCHEMBL5077818 | 0.82 | ALDH1A1 (0.61) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106106473-A | A kind of compositions preventing and treating Caulis et Folium Brassicae capitatae diamondback moth and preparation method thereof | 殷佩琼 | 2016-11-16 | — | — | CN | claimed |
| CN-107998897-A | A kind of surface hydrophilic modification method of Pvdf Microporous Hollow Fiber Membrane | 北京化工大学 | 2018-05-08 | — | — | CN | disclosed |
| CN-107589254-A | A kind of manufacture method of immunoliposome complex nano-particle biochip and application | 奈尔公司 | 2018-01-16 | — | — | CN | disclosed |
| CN-106106473-A | A kind of compositions preventing and treating Caulis et Folium Brassicae capitatae diamondback moth and preparation method thereof | 殷佩琼 | 2016-11-16 | — | — | CN | disclosed |
| EP-2171043-B1 | TREATMENT OF DISEASES AND DISORDERS USING SELF-RENEWING COLONY FORMING CELLS CULTURED AND EXPANDED IN VITRO | GARNET BIOTHERAPEUTICS INC (US) | 2015-03-18 | — | — | EP | disclosed |
| US-20140099329-A1 | TREATMENT OF DISEASES AND DISORDERS USING SELF-RENEWING COLONY FORMING CELLS CULTURED AND EXPANDED IN VITRO | GARNET BIOTHERAPEUTICS, INC. (US) | 2014-04-10 | — | — | US | disclosed |
| US-20140086884-A1 | TREATMENT OF DISEASES AND DISORDERS USING SELF-RENEWING COLONY FORMING CELLS CULTURED AND EXPANDED IN VITRO | Gamet BioTherapeutics, Inc., (US) | 2014-03-27 | — | — | US | disclosed |
| US-20130266542-A1 | Compositions and Methods of Using Living and Non-Living Bioactive Devices with Components Derived From Self-Renewing Colony Forming Cells Cultured and Expanded In Vitro | Garnet BioThereapeutics, Inc. (US) | 2013-10-10 | — | — | US | disclosed |
| US-20130259837-A1 | Compositions and Methods of Using Living and Non-Living Bioactive Devices with Components Derived From Self-Renewing Colony Forming Cells Cultured and Expanded In Vitro | GARNET BIOTHERAPEUTICS INC (US) | 2013-10-03 | — | — | US | disclosed |
| EP-2575441-A1 | COMPOSITIONS AND METHODS OF USING LIVING AND NON-LIVING BIOACTIVE DEVICES WITH COMPONENTS DERIVED FROM SELF-RENEWING COLONY FORMING CELLS CULTURED AND EXPANDED IN VITRO | Garnet BioTherapeutics, Inc (US) | 2013-04-10 | — | — | EP | disclosed |
| US-8354370-B2 | Administering a biological composition or compositions isolated from self-renewing colony forming somatic cell growth medium to treat diseases and disorders | GARNET BIOTHERAPEUTICS, INC. (US) | 2013-01-15 | — | — | US | disclosed |
| US-20120156192-A1 | Treatment of Diseases and Disorders Using Self-Renewing Colony Forming Cells Cultured and Expanded In Vitro | GARNET BIOTHERAPEUTICS, INC. (US) | 2012-06-21 | — | — | US | disclosed |
| US-20120148544-A1 | Treatment of Diseases and Disorders Using Self-Renewing Colony Forming Cells Cultured and Expanded In Vitro | GARNET BIOTHERAPEUTICS, INC. (US) | 2012-06-14 | — | — | US | disclosed |
| US-20120121555-A1 | Compositions and Methods of Using Living and Non-Living Bioactive Devices with Components Derived From Self-Renewing Colony Forming Cells Cultured and Expanded In Vitro | GARNET BIOTHERAPEUTICS, INC. (US) | 2012-05-17 | — | — | US | disclosed |
| US-20120003188-A1 | Compositions and Methods of Using Living and Non-Living Bioactive Devices with Components Derived from Self-Renewing Colony Forming Cells Cultured and Expanded In Vitro | GARNET BIOTHERAPEUTICS, INC. (US) | 2012-01-05 | — | — | US | disclosed |
| WO-2011150398-A1 | COMPOSITIONS AND METHODS OF USING LIVING AND NON-LIVING BIOACTIVE DEVICES WITH COMPONENTS DERIVED FROM SELF- RENEWING COLONY FORMING CELLS CULTURED AND EXPANDED IN VITRO | GARNET BIOTHERAPEUTICS, INC (US) | 2011-12-01 | — | — | WO | disclosed |
| EP-2171043-A1 | TREATMENT OF DISEASES AND DISORDERS USING SELF-RENEWING COLONY FORMING CELLS CULTURED AND EXPANDED IN VITRO | Garnet BioTherapeutics, Inc (US) | 2010-04-07 | — | — | EP | disclosed |
| US-20090053183-A1 | Treatment of Diseases and Disorders Using Self-Renewing Colony Forming Cells Cultured and Expanded In Vitro | NEURONYX INC. (US) | 2009-02-26 | — | — | US | disclosed |
| WO-2008156728-A1 | TREATMENT OF DISEASES AND DISORDERS USING SELF-RENEWING COLONY FORMING CELLS CULTURED AND EXPANDED IN VITRO | NEURONYX, INC. (US) | 2008-12-24 | — | — | WO | disclosed |