Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 5/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.48 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.48 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.48 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PLAU | P00749 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | CCNC | P24863 | 1/20 | 0.44 |
| ▸ | CDK8 | P49336 | 1/20 | 0.44 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.43 |
| ▸ | IP6K3 | Q96PC2 | 1/20 | 0.43 |
| ▸ | IP6K2 | Q9UHH9 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ACSS2 | Q9NR19 | 2/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12132593 | 0.85 | PLAU (0.47) | PLK1HDAC8HDAC6HDAC2THRB | |
| SCHEMBL29951666 | 0.85 | ERN1 (0.54) | PLK1HDAC8HDAC6HDAC2THRB | |
| SCHEMBL15920688 | 0.85 | PLK1 (0.47) | PLK1HDAC8HDAC6HDAC2THRB | |
| SCHEMBL29952332 | 0.85 | PLK1 (0.47) | PLK1HDAC8HDAC6HDAC2THRB | |
| SCHEMBL20017813 | 0.84 | PLK1 (0.46) | PLK1HDAC8HDAC6HDAC2THRB | |
| SCHEMBL25128750 | 0.78 | KMT2A (0.45) | THRBSMN1; SMN2HPGDHTTTDP1 | |
| SCHEMBL268917 | 0.77 | TDP1 (0.42) | THRBSMN1; SMN2HPGDTSHRHTT | |
| SCHEMBL17747083 | 0.77 | ALDH1A1 (0.58) | SMN1; SMN2HPGDHTTTDP1CA2 | |
| SCHEMBL4918747 | 0.75 | ALDH1A1 (0.52) | THRBSMN1; SMN2HPGDTSHRTDP1 | |
| SCHEMBL29941258 | 0.75 | ALDH1A1 (0.52) | THRBSMN1; SMN2HPGDTSHRTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3974462-B1 | POLYETHYLENE GLYCOL DERIVATIVE, PREPARATION METHOD THEREFOR, AND POLYETHYLENE GLYCOL HYDROGEL ENABLING FAST CROSSLINKING REACTION | CHANGCHUN INST APPLIED CHEMISTRY CAS (CN) | 2024-04-17 | — | — | EP | disclosed |
| US-20230002554-A1 | POLYETHYLENE GLYCOL DERIVATIVE, PREPARATION METHOD THEREOF, AND POLYETHYLENE GLYCOL HYDROGEL CAPABLE OF PRODUCING A RAPID CROSSLINKING REACTION | CHANGCHUN INSTITUTE OF APPLIED CHEMISTRY CHINESE ACADEMY OF SCIENCES (CN) | 2023-01-05 | — | — | US | disclosed |
| EP-3974462-A1 | POLYETHYLENE GLYCOL DERIVATIVE, PREPARATION METHOD THEREFOR, AND POLYETHYLENE GLYCOL HYDROGEL ENABLING FAST CROSSLINKING REACTION | Changchun Institute Of Applied Chemistry Chinese Academy Of Sciences (CN) | 2022-03-30 | — | — | EP | disclosed |
| WO-2021237864-A1 | POLYETHYLENE GLYCOL DERIVATIVE, PREPARATION METHOD THEREFOR, AND POLYETHYLENE GLYCOL HYDROGEL ENABLING FAST CROSSLINKING REACTION | 中国科学院长春应用化学研究所 | 2021-12-02 | — | — | WO | disclosed |