Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PHGDH | O43175 | 1/20 | 0.38 |
| ▸ | MGLL | Q99685 | 1/20 | 0.38 |
| ▸ | SHMT2 | P34897 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.36 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.36 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16515908 | 0.81 | L3MBTL3 (0.42) | SHMT2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL23367198 | 0.81 | TP53 (0.38) | PHGDHMGLLSHMT2MEN1KMT2A | |
| SCHEMBL4014698 | 0.77 | L3MBTL3 (0.42) | SHMT2ALDH1A1CHRNA7CHRM1HRH3 | |
| SCHEMBL31707149 | 0.76 | L3MBTL3 (0.49) | SHMT2CHRM1HRH3L3MBTL3L3MBTL1 | |
| SCHEMBL31664986 | 0.74 | CHRM1 (0.46) | ALDH1A1CHRNA7CHRM1HRH3L3MBTL3 | |
| SCHEMBL21885561 | 0.73 | TP53 (0.44) | SHMT2ALDH1A1CHRNA7CHRM1HRH3 | |
| SCHEMBL4550270 | 0.73 | TP53 (0.44) | SHMT2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL24402953 | 0.73 | TP53 (0.44) | SHMT2MEN1KMT2AALDH1A1HPGD | |
| SCHEMBL13767850 | 0.73 | CHRNA7 (0.46) | ALDH1A1CHRNA7CHRM1HRH3L3MBTL3 | |
| SCHEMBL30365109 | 0.73 | TP53 (0.44) | SHMT2ALDH1A1CHRNA7CHRM1HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021239058-A1 | FUSED TRICYCLIC COMPOUND, PHARMACEUTICAL COMPOSITION THEREOF, AND USE THEREOF | 劲方医药科技(上海)有限公司 | 2021-12-02 | — | — | WO | disclosed |