Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 7/20 | 0.48 |
| ▸ | KDM5A | P29375 | 1/20 | 0.43 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.43 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 5/20 | 0.43 |
| ▸ | RAB9A | P51151 | 5/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | CDK2 | P24941 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NAMPT | P43490 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.39 |
| ▸ | CCNB2 | O95067 | 2/20 | 0.39 |
| ▸ | CDK1 | P06493 | 2/20 | 0.39 |
| ▸ | CCNB1 | P14635 | 2/20 | 0.39 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.39 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24071281 | 0.80 | SCN10A (0.46) | KDM5AKDM4CKDM5BNPC1RAB9A | |
| SCHEMBL30492126 | 0.80 | SCN10A (0.46) | KDM5AKDM4CKDM5BNPC1RAB9A | |
| SCHEMBL24071266 | 0.77 | ALOX15 (0.43) | ALOX15NPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL21677294 | 0.75 | NPC1 (0.50) | ALOX15NPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL24071161 | 0.70 | CDK5 (0.50) | ALOX15KDM5AKDM4CKDM5BNPC1 | |
| SCHEMBL27158570 | 0.68 | CCNB2 (0.67) | KDM5AKDM4CKDM5BCCNB2CDK1 | |
| SCHEMBL16700671 | 0.68 | ALOX15 (0.54) | ALOX15NPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL14688333 | 0.67 | ALOX15 (1.00) | ALOX15NPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL16321180 | 0.66 | ALOX15 (0.62) | ALOX15NPC1RAB9ASMN1; SMN2CDK2 | |
| SCHEMBL16320825 | 0.66 | ALOX15 (0.58) | ALOX15NPC1RAB9ASMN1; SMN2CDK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021242955-A1 | FUSED AZOLE HETEROCYCLES AS AHR ANTAGONISTS | SENDA BIOSCIENCES, INC. (US) | 2021-12-02 | — | — | WO | disclosed |