Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.50 |
| ▸ | RAB9A | P51151 | 6/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 5/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.50 |
| ▸ | CDK2 | P24941 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | ITK | Q08881 | 9/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | NAMPT | P43490 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21677358 | 0.83 | GRM4 (0.52) | NPC1RAB9ASMN1; SMN2ITK | |
| SCHEMBL21629670 | 0.79 | NPC1 (0.48) | NPC1RAB9ASMN1; SMN2CDK2ITK | |
| SCHEMBL21677355 | 0.77 | ITK (0.59) | NPC1RAB9AALOX15SMN1; SMN2L3MBTL1 | |
| SCHEMBL21677248 | 0.77 | ITK (0.42) | NPC1RAB9AITKMEN1KMT2A | |
| SCHEMBL20482953 | 0.77 | GRM1 (0.49) | NPC1RAB9ASMN1; SMN2ITKMEN1 | |
| SCHEMBL21629657 | 0.76 | ITK (0.41) | NPC1RAB9ACDK2L3MBTL1ITK | |
| SCHEMBL24071106 | 0.75 | ALOX15 (0.48) | NPC1RAB9AALOX15SMN1; SMN2CDK2 | |
| SCHEMBL20482663 | 0.73 | ITK (0.42) | NPC1RAB9AALOX15L3MBTL1ITK | |
| SCHEMBL21657925 | 0.71 | CASP3 (0.51) | RAB9AALOX15SMN1; SMN2ITKMEN1 | |
| SCHEMBL21657836 | 0.69 | CASP3 (0.67) | NPC1RAB9AALOX15ITKMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200031805-A1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | PHENEX PHARMACEUTICALS AG (DE) | 2020-01-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200031805-A1 | ARYL HYDROCARBON RECEPTOR (AHR) MODULATOR COMPOUNDS | AHR, ARNT, AIPL1 | NPC1 991/4885RAB9A 4101/4885ALOX15 339/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.